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Traditional Chinese medicine composition with effect of treating metabolic syndrome and preparation method and application of traditional Chinese medicine composition

A technology for metabolic syndrome and composition, which is applied in the field of traditional Chinese medicine compound composition and preparation thereof, can solve the problems of lack of clinical efficacy research, treating the symptoms but not the root cause, and inconsistent treatment, and achieves safe and reliable medication, less toxic and side effects, The effect of strict medication

Active Publication Date: 2018-05-25
JIANGSU PROVINCIAL HOSPITAL OF TCM +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many drugs for the treatment of metabolic syndrome. Although the western medicines used clinically have certain curative effects, most of them have relatively large adverse reactions, such as rebound after drug withdrawal, liver and kidney damage in patients, rhabdomyolysis and other side effects. It does not cure the root cause, but traditional Chinese medicine has its unique advantages in the treatment of metabolic syndrome. There are many prescriptions for the prevention and treatment of metabolic syndrome in traditional Chinese medicine, and the curative effect is relatively long-lasting, and most of them have no obvious side effects. There is a lack of systematic and comprehensive clinical efficacy research on proven prescriptions, and the basis of traditional Chinese medicine prescriptions is different, and the treatment principles are not uniform. Therefore, based on traditional Chinese medicine, according to the pathogenesis of metabolic syndrome, actively seek and work hard to explore effective and non-toxic treatments for this disease. Portable medicine is of great significance

Method used

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  • Traditional Chinese medicine composition with effect of treating metabolic syndrome and preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
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Effect test

Embodiment 1

[0030] 1. A traditional Chinese medicine compound composition with the effect of treating metabolic syndrome, which is made of the following raw materials in parts by weight: 15g Radix Pseudostellariae, 15g Ophiopogon japonicus, 10g Salvia miltiorrhiza, 10g Sophora japonica, 10g chrysanthemum, 10g honeysuckle, white Chine root 10g, radish seed 10g.

[0031] 2. The preparation method of the compound Chinese medicine composition with the effect of treating metabolic syndrome according to the present invention, which comprises the following steps:

[0032] (1) According to parts by weight, take 15g of heterophylla, 15g of Ophiopogon japonicus, 10g of salvia miltiorrhiza, 10g of Huai Mi, 10g of chrysanthemum, 10g of honeysuckle, and 10g of Imperata rhizome. hour, combine the extracts, concentrate to obtain the extract, and set aside;

[0033] (2) Get radish seed 10g by parts by weight, use the ethanol reflux extraction of 8 times of raw materials weight amount to extract 2 times,...

Embodiment 2

[0036] 1. A traditional Chinese medicine compound composition with the effect of treating metabolic syndrome, which is made of the following raw materials in parts by weight: 45g Radix Pseudostellariae, 45g Ophiopogon japonicus, 30g Salvia miltiorrhiza, 30g Huai Mi, 30g chrysanthemum, 30g honeysuckle, white Chine root 30g, radish seed 30g.

[0037] 2. The preparation method of the compound Chinese medicine composition with the effect of treating metabolic syndrome according to the present invention, which comprises the following steps:

[0038] (1) Take 45g of Radix Pseudostellariae, 45g of Ophiopogon japonicus, 30g of Salvia miltiorrhiza, 30g of Huai Mi, 30g of chrysanthemum, 30g of honeysuckle, 30g of Imperata rhizome in parts by weight, add water 8 times the weight of the medicinal material, and reflux for extraction twice, each time for 2 hours , combine the extracts, concentrate to obtain the extract, and set aside;

[0039] (2) Get radish seed 30g by parts by weight, us...

Embodiment 3

[0042] 1. A traditional Chinese medicine compound composition with the effect of treating metabolic syndrome, which is made of the following raw materials in parts by weight: Radix heterophylla 30g, Ophiopogon japonicus 30g, Salvia miltiorrhiza 20g, Huai Mi 20g, chrysanthemum 20g, honeysuckle 20g, white Chine root 20g, radish seed 20g.

[0043]2. The preparation method of the compound Chinese medicine composition with the effect of treating metabolic syndrome according to the present invention, which comprises the following steps:

[0044] (1) Take 30g of Radix Pseudostellariae, 30g of Ophiopogon japonicus, 20g of Salvia miltiorrhiza, 20g of Sophora japonica, 20g of chrysanthemum, 20g of honeysuckle, 20g of Imperata rhizome in parts by weight, add water 12 times the weight of the medicinal materials and reflux to extract twice, 1 hour each time , combine the extracts, concentrate to obtain the extract, and set aside;

[0045] (2) Take radish seed 20g by parts by weight, reflu...

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Abstract

The invention discloses a traditional Chinese medicine composition with effect of treating metabolic syndrome and a preparation method and application of the traditional Chinese medicine composition.The traditional Chinese medicine composition with effect of treating metabolic syndrome is prepared from the following components in parts by weight: 15-45 parts of Radix Pseudostellariae, 15-45 partsof Radix Ophiopogonis, 10-30 parts of Radix Salviae Miltiorrhizae, 10-30 parts of Flos Sophorae Immaturus, 10-30 parts of Flos Chrysanthemi, 10-30 parts of Flos Lonicerae, 10-30 parts of Rhizoma Imperatae and 10-30 parts of Semen Raphani. Proportioning of the formula is implemented by a theory of treatment based on syndrome differentiation, a clinical experiment result shows that the traditionalChinese medicine composition has combined actions of multiple links and multiple targets, can correct glucose and lipid metabolism disorder of patients with the metabolic syndrome, has effects of reducing blood glucose, blood fat and blood pressure, and improving insulin resistance, and can be used for preventing and treating the metabolic syndrome, and the clinical experiment result shows that the traditional Chinese medicine composition does not have adverse reactions when orally taken for a long time, and is safe to use.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicine, in particular to a compound traditional Chinese medicine composition capable of treating metabolic syndrome, a preparation method and application thereof. Background technique [0002] Metabolic syndrome (MS) is a group of clinical syndromes with central obesity, hypertension, dyslipidemia, abnormal glucose metabolism and other metabolic abnormal clusters as the connotation, and insulin resistance as the common pathophysiological basis. In recent years, the clinical incidence of MS has been increasing, and the risk of cardiovascular and cerebrovascular diseases in this population has increased by 3 times, seriously infringing on the physical and mental health of patients. [0003] At present, there are many drugs for the treatment of metabolic syndrome. Although the western medicines used clinically have certain curative effects, most of them have relatively large adverse reactions, such...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P3/10A61P3/06A61P9/12A61P3/04A61P5/50
CPCA61K36/8968A61K36/899A61K36/287A61K36/31A61K36/355A61K36/36A61K36/489A61K36/537A61K2236/331A61K2236/333A61K2236/53A61K2300/00
Inventor 方祝元王志林严士海严冬耿志荣
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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