Flavoring tablet of children medicine and preparation method

A technology for children's medication and flavor correction, which is applied in the direction of medical formula, medical preparations of non-active ingredients, pill delivery, etc., and can solve delayed treatment, discomfort, and even vomiting, no major progress in flavoring agents and flavoring technology, etc. problems, to achieve great social and economic benefits, simple preparation process, and good application prospects

Active Publication Date: 2018-03-02
HEBEI UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Most drugs, especially traditional Chinese medicine preparations, often have unpleasant tastes, such as bitter, astringent, sour, etc. When patients eat them, they will cause taste discomfort and even vomiting, especially in children, because the distribution of taste buds is more complex. It is widely used, more sensitive to taste, and its compliance is poor, and the treatment is often delayed because children refuse to cooperate with it, which limits its use in children
Flavoring agents can improve or shield the bitterness of medicines, making it difficult for patients to perceive the strong bitterness of medicines (or other peculiar smells such as pungent, sour, etc.), but most of the flavoring effects of existing flavoring agents and flavoring technologies are poor, or not Applicable to children's medicines, there is no major progress in flavoring agents and flavoring technologies related to children's medicines

Method used

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  • Flavoring tablet of children medicine and preparation method
  • Flavoring tablet of children medicine and preparation method
  • Flavoring tablet of children medicine and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] (1) Treat the miracle fruit to prepare the miracle fruit powder. The miracle fruit used is fresh fruit, specifically:

[0030] Weigh the fresh miracle fruit, wash it with pure water, smash it into small pieces and then transfer it to a small beaker, add an equal volume of pure water, use a homogenizer to homogenize the slurry with uniform color and fine particles in the solution, and then use Vacuum pump for suction filtration, after the filtrate is left to settle, recover the supernatant, continue to filter the remaining precipitate containing white powdery solids and recover the supernatant, repeat several times until there is no obvious white precipitate in the suction filtrate, and then repeatedly The recovered supernatant is mixed with the last suction filtrate to obtain a miracle fruit slurry; the miracle fruit slurry is dried under reduced pressure at 40-45° C., and then ultrafinely pulverized to obtain a miracle fruit powder.

[0031] (2) Extract and concentrate...

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PUM

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Abstract

The invention discloses a flavoring tablet of a children medicine. The flavoring tablet is prepared by the following steps of using synsepalum dulcificum fruit and fructus momordicae as raw materialsto respectively prepare synsepalum dulcificum fruit powder and fructus momordicae powder, and then mixing according to a certain ratio, so as to obtain flavoring powder; weighing the equal amounts offlavoring powder and auxiliary material according to a mass ratio of 1:1, firstly mixing 1 / 3 of flavoring powder and 3 / 4 of auxiliary material, then using 20% ethyl alcohol as a wetting agent, using the balance of flavoring powder as a filling agent, and granulating, wherein the auxiliary material is a mixture of L-HPC (low-substituted hydroxypropyl cellulose), PVPP (polyvinylpolypyrrolidone), CMS-Na (sodium carboxymethyl starch) and MCC (microcrystalline cellulose) according to a mass ratio of 10:8:3:6; drying the prepared particles, granulating, adding the left auxiliary material and magnesium stearate, and tabletting, so as to obtain the flavoring tablet. The flavoring tablet prepared by the experiment has the advantages that the synsepalum dulcificum fruit and the fructus momordicae are used as the raw materials and are added into the particular type and ratio of auxiliary material to prepare the flavoring tablet, and the flavoring tablet is applied to the children medicine for taste interference; the effect is outstanding, the mouth feel of the medicine can be effectively improved, the corresponding pain is relieved when the children medicine is taken, the preparation technology is simple, the flavoring tablet is suitable for industrial production, and the good application prospect and larger social and economic benefits are realized.

Description

technical field [0001] The invention relates to a plant-based traditional Chinese medicine preparation, in particular to a flavor-correcting tablet for children and a preparation method thereof. Background technique [0002] Most drugs, especially traditional Chinese medicine preparations, often have unpleasant tastes, such as bitter, astringent, sour, etc. When patients eat them, they will cause taste discomfort and even vomiting, especially in children, because the distribution of taste buds is more complex. It is widely used, more sensitive to taste, and its compliance is poor. Children often delay treatment because they refuse to take it together, which limits its use in children. Flavoring agents can improve or shield the bitterness of medicines, making it difficult for patients to perceive the strong bitterness of medicines (or other peculiar smells such as pungent, sour, etc.), but most of the flavoring effects of existing flavoring agents and flavoring technologies a...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K47/46A61K47/38A61K47/36A61K47/32
CPCA61K9/2027A61K9/2054A61K9/2059A61K9/2068
Inventor 张国伟李林俸刘琛田旭彤刘雪莲
Owner HEBEI UNIVERSITY
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