Mass spectrometer, ion optical device and method for ion operation in mass spectrometer

Abstract

The present invention provides a mass spectrometer, an ion optical device and a method for ion operation in a mass spectrometer. The mass spectrometer comprises: a mass analyzer; an ion guidance device which comprises two sets of electrode arrays arranged in parallel to each other, each set of the annular electrode array is formed by at least two concentrically arranged annular electrodes or formed by at least three linear electrodes distributed in a radiation mode; and a power device configured to apply voltage at the at least part of the annular electrodes to form a radio frequency electricfield and a direct current electric field, ions are stored at an area between the two sets of arrays through the frequency electric field and direct current electric field, and the ions can be controlled to be released along a radial direction according to a predetermined mass-to-charge ratio requirement and can be controlled to depart from the ion guidance device to enter the mass analyzer for mass analysis. According to the technical scheme, high ion utilization efficiency and large ion storage capacity can be realized, and miniaturization of an instrument can be realized.

Description

technical field [0001] The invention relates to the technical field of mass analysis, in particular to a mass spectrometer, an ion optical device and a method for operating ions in the mass spectrometer. Background technique [0002] The typical working mode of quadrupole-orthogonal time-of-flight mass spectrometer is: ions generated by the ion source, through a series of vacuum interfaces and ion guide devices, enter the quadrupole for mass selection, and the selected parent ions enter the collision chamber After dissociation, many product ions are produced. The product ions enter the pulse acceleration area in front of the flight chamber and are accelerated in an orthogonal manner. Due to the different flight times of the ions, a high-resolution and high-precision mass spectrum is generated. Among them, the quadrupole usually works continuously in a scanning manner, while the time-of-flight mass spectrometer works in a pulsed manner. If no modulation is made to the ions i...

AI Technical Summary

Problems solved by technology

[0008] In view of the above-mentioned shortcomings of the prior art, the object of the present invention is to provide a mass spectrometer, an ion optical device and a method for operating ions in the mass spectrometer, so as to solve the gap between ion utilization efficiency and instrument volume in the mass spectrometer in the prior art. Balance and other issues

Images