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Dog and cat pill containing antiparasitic drug and attractant

An anti-parasite and food attractant technology, applied in the field of pills and pills with food attractant effect, can solve problems such as difficulty in administration, achieve excellent food attractant effect, low production cost, and simple preparation method

Inactive Publication Date: 2017-12-22
中农华威生物制药(湖北)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention proposes an anti-parasitic pill for dogs and cats containing an attractant and a preparation method thereof. The preparation method of the pill proposed by the present invention is simple, easy to operate, does not require expensive equipment, and has low production cost. The method is applied The prepared pill has an excellent food-attracting effect, and overcomes the defect that the commercially available preparations are difficult to administer

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1, preparation contains the pill core containing praziquantel 100mg / grain

[0026] The drug-containing pill core contains 0.5kg of praziquantel, 2.75kg of starch, 0.25kg of sodium carboxymethyl starch, 2.5kg of suet oil residue, 2.7kg of pig liver powder, 43.5g of potassium sorbate, 86g of sodium glutamate, and 5g of sodium saccharin , NaCl 136g.

[0027] The preparation process is as follows: mix 0.75kg starch with 0.25kg sodium carboxymethyl starch, add 3kg water, make a paste at 75-90°C, then add oil residue, praziquantel and pig liver powder, and mix well , then add the remaining starch and other remaining ingredients, and put them into the automatic pill machine (WK-240 type), through full stirring, extrusion, kneading, to make plastic pills that are not sticky and not loose, through the screw The rods are extruded into pellets, and the pellets are further made into spherical or ellipsoidal pellets through double-roller (double-rubbing wheel) cutters. ...

Embodiment 2

[0028] Embodiment 2, preparation contains the pill of praziquantel 100mg / grain

[0029]The drug-containing pill core contains 0.5kg of praziquantel, 2.75kg of starch, 0.25kg of sodium carboxymethyl starch, 2.5kg of suet oil residue, 2.7kg of chicken liver powder, 43.5g of potassium sorbate, 86g of sodium glutamate, and 5g of sodium saccharin , NaCl 136g. The preparation process is divided into two steps, first preparing the core of the pill containing the medicine, and then coating the core of the medicine containing the pill with the coating material containing the attractant.

[0030] Concrete preparation process is as follows:

[0031] (1) Preparation of drug-containing pill core: Mix 0.75kg starch and 0.25kg sodium carboxymethyl starch, add 3kg water, make a paste at 75-90°C, then add oil residue, praziquantel and chicken liver powder , fully mixed, then add the remaining starch and other remaining ingredients, and put them into the automatic pill machine (WK-240 type) ...

Embodiment 3

[0035] Embodiment 3, prepare the dog medicine pill containing praziquantel 100mg / grain

[0036] The formula containing the pill core is composed of praziquantel 200g, glycerin 80g, carmellose calcium 800g, sucrose 1000g, polyvinylpyrrolidone 160g, potassium sorbate 12g, chocolate flavoring agent 23g, sodium glutamate 23g , sodium saccharin 1g, NaCl33g, sodium lauryl sulfate 115g. The specific preparation process is divided into two steps. First, the drug-containing pellet core is prepared, and then the drug-containing pellet core is coated with a coating material containing an attractant. The specific preparation process is as follows:

[0037] (1) Preparation of drug-containing pill core: Weigh each component according to the formula, put it into a plastic basin, add 500-700ml of water while stirring, fully squeeze and knead to make a plastic mass that is not sticky and not loose , and then use a small multi-functional pill making machine (Lg-18 type) to press the cake and ...

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Abstract

The present invention provides a dog and cat pill containing an antiparasitic drug and an attractant. The pill has a coating layer structure, and cannot have a coating layer, wherein the pill with the coating layer structure comprises a drug-containing pill core and a drug-free coating layer coated on the surface of the pill core, one or a plurality of the coating layers can exist, the coating layer at least contains an attractant or a flavoring agent, the pill at least contains an antiparasitic drug or at least contains a microcapsule containing an antiparasitic drug, the antiparasitic drug accounts for 0.05-20% of the weight of the pill, the attractant accounts for 1-65% of the weight of the pill, the pill at least contains an adhesive, the adhesive accounts for 4-45% of the weight of the pill, and the pill can further contain a disintegrant, a preservative, an antioxidant, a coloring agent, a wetting agent and other additives. According to the present invention, the pill has characteristics of easy preparation, low cost and good palatability, wherein the active feeding rate of dog and cat on the pill can achieve more than 90%.

Description

technical field [0001] The invention relates to the preparation technology of veterinary drug preparations, in particular to a pill with food-attracting effect for preventing and treating parasitic diseases of dogs and cats, and the pill is also called pill. Background technique [0002] Dogs and cats are susceptible to a variety of parasites, such as nematodes, tapeworms, trematodes, protozoa and ectoparasites, and most parasites can be further transmitted to humans and other animals (pigs, cattle, sheep, etc.), such as Echinococcus granulosus The main intermediate hosts are domestic dogs, herding dogs, and canines such as foxes. Therefore, strengthening the regular deworming of dogs can not only prevent parasitic diseases in dogs, but more importantly, prevent the further spread of diseases. Presently commercially available preparations for preventing and treating parasitic diseases in dogs and cats include tablets, injections and external preparations (such as pouring ag...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/42A61K9/30A61K31/4985A61K31/7048A61K31/27A61K31/506A61K31/4184A61K31/167A61P33/10A61P33/14
Inventor 游锡火王玉万翁志飞王金萍韩可可任雅楠李莹李蕾沈力
Owner 中农华威生物制药(湖北)有限公司
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