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Preparation method for compound berry composition capable of resisting acute radiation injury

A technology of radiation damage and manufacturing method, which is applied in the direction of drug combination, medical preparations containing active ingredients, anti-toxins, etc., and can solve the problems of no unified and effective solution, radiation damage, etc.

Inactive Publication Date: 2017-12-01
山东尚美健康产业技术发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] As the incidence of tumors increases, radiation therapy is becoming more and more common! There is currently no uniform and effective solution to the damage caused by radiation therapy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] Example 1: Red raspberries, blackberries, mulberries, blackcurrants, and medlars were mixed in proportions of 30%, 25%, 22%, 13%, and 10% respectively by weight, and put into the fermentation tank after being frozen at low temperature In the fermentation tank, the temperature is gradually increased to 17°C, the residual sugar content is controlled below 4g / L at the end of the fermentation, the fermented liquid and the skin residue are separated by filtration to obtain the skin residue containing fruit seed material, and the skin residue is Squeeze, further filter out the juice, and then dry the squeezed leather residue for three hours at a drying temperature of 100°C. The dried leather residue is naturally aired, and then crushed after drying. The second drying, the drying time is one hour, and the drying temperature is 100°C. The skin residue after the second drying is crushed and passed through a 200-mesh sieve to obtain the berry seed powder.

[0053] The black raspberr...

Embodiment 2

[0067] Example 2: Red raspberries, blackberries, mulberries, blackcurrants, and medlars were mixed in proportions of 33%, 23%, 25%, 10%, and 9% respectively by weight, and put into the fermentation tank after being frozen at low temperature In the fermenter, the temperature is gradually increased to 17°C, the residual sugar content is controlled below 4g / L at the end of the fermentation, the fermented liquid and the skin residue are separated by filtration to obtain the skin residue containing fruit seed material, and the skin residue is Squeeze, further filter out the juice, and then dry the squeezed leather residue for three hours at a drying temperature of 100°C. The dried leather residue is naturally aired, and then crushed after drying. The second drying, the drying time is one hour, and the drying temperature is 100°C. The skin residue after the second drying is crushed and passed through a 200-mesh sieve to obtain the berry seed powder.

[0068] The black raspberry, pomegr...

Embodiment 3

[0082] Example 3: Red raspberries, blackberries, mulberries, blackcurrants, and medlars were mixed in proportions of 35%, 21%, 24%, 15%, and 5% by weight, respectively, and put into the fermentation tank after being frozen at low temperature In the fermenter, the temperature is gradually increased to 17°C, the residual sugar content is controlled below 4g / L at the end of the fermentation, the fermented liquid and the skin residue are separated by filtration to obtain the skin residue containing fruit seed material, and the skin residue is Squeeze, further filter out the juice, and then dry the squeezed leather residue for three hours at a drying temperature of 100°C. The dried leather residue is naturally aired, and then crushed after drying. The second drying, the drying time is one hour, and the drying temperature is 100°C. The skin residue after the second drying is crushed and passed through a 200-mesh sieve to obtain the berry seed powder.

[0083] The black raspberry, pomeg...

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PUM

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Abstract

The invention discloses a preparation method for compound berry composition capable of resisting acute radiation injury. The preparation method comprises the following steps: A: mixing the berry composition at a ratio, carrying out low-temperature freezing, putting into a fermentation tank, gradually raising the temperature, and controlling the temperature to be 15-20DEG C; B: carrying out filtering separation on liquid fermented in step A and peel residues; C: squeezing the peel residues separated in step B; D: drying the peel residues squeezed in step C at the temperature of 100DEG C for 2.5-3h; E: naturally airing the peel residues dried and obtained in step D, and breaking after airing; F: carrying out secondary drying on the peel residues broken in step E at the temperature of 100DEG C, wherein drying time is one hour; G: smashing the second drying peel residues obtained in step F, and sieving in a 200-mesh sieve to obtain berry seed powder; H: respectively carrying out freeze-drying and smashing on the fruits of black raspberries, blueberries, pomegranate and hovenia acerba, and sieving by a 200-mesh sieve to obtain the freeze-drying fruit powder of each fruit; I: mixing the berry seed powder obtained in step G with the freeze-drying fruit powder of each fruit.

Description

Technical field [0001] The present technology relates to a berry mixture, in particular to a berry mixture for reducing acute radiation damage. Background technique [0002] With the increase in the incidence of tumors, radiotherapy has become more and more common! There is currently no uniform and effective solution to the damage caused by radiotherapy. After radiotherapy, a large number of reactive oxygen species are produced in the patient's body, which play an important role in cell damage caused by ionizing radiation, leading to DNA strand breaks, lipid peroxidation, and protein denaturation. If oxidative stress exceeds the body's self-regulation ability, hemoglobin, cell membrane and enzymes will undergo degenerative changes, which will lead to cellular dysfunction. Summary of the invention [0003] In response to the great harm caused by acute radiation to the human body, the human body will produce a large amount of reactive oxygen species (ROS) after ionizing radiation. ...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P39/00
CPCA61K36/185A61K36/605A61K36/73A61K36/815A61K2300/00
Inventor 季道远苑伟刘明磊李佳少
Owner 山东尚美健康产业技术发展有限公司
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