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Asparagus extract and preparation method and application thereof

An asparagus extract and asparagus technology are applied in the field of biomedicine, can solve problems such as dependence, achieve no drug dependence side effects, and treat cardiovascular and cerebrovascular diseases.

Inactive Publication Date: 2017-07-21
广州市天河华南发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are two main types of drugs for the treatment of cardiovascular and cerebrovascular diseases, one is simply dilating blood vessels, and the other is thrombolysis and fat-dissolving. side effects of drug dependence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The preparation method of the asparagus extract comprises the following steps: crushing the dried asparagus aboveground stems to 25 meshes to obtain dry asparagus powder; adding boiling water to the dry asparagus powder with a solid-liquid ratio of 1:17, extracting with boiling water for 2.2 hours, and filtering to obtain the extract; Place the extract for 14 hours, suction filter, and dry the filtrate to obtain the crude asparagus extract; add boiling water and saturated lime water to the crude asparagus extract, adjust the pH to 7.5, and keep the liquid in a boiling state until the crude asparagus extract is completely Dissolve, filter, and obtain the filtrate. The ratio of crude asparagus extract, boiling water, and saturated lime water is 1:98:30; use hydrochloric acid solution to adjust the pH value of the filtrate to 4.6, let it stand for 60 minutes, suction filter, and wash the filtrate with water 3 times, dried to obtain asparagus extract.

[0019] In this embod...

Embodiment 2

[0023] The preparation method of the asparagus extract comprises the following steps: crushing the dried asparagus aerial stems to 27 meshes to obtain dry asparagus powder; adding boiling water to the dry asparagus powder with a solid-liquid ratio of 1:18, extracting with boiling water for 2.3 hours, and filtering to obtain the extract; Place the extract for 15 hours, suction filter, and dry the filtrate to obtain the crude asparagus extract; add boiling water and saturated lime water to the crude asparagus extract, adjust the pH to 7.8, and keep the liquid in a boiling state until the crude asparagus extract is completely Dissolve, filter, obtain filtrate, the ratio of crude asparagus extract, boiling water, and saturated lime water is 1:99:32; use hydrochloric acid solution to adjust the pH value of the filtrate to 4.3, let stand for 60min, suction filter, and wash the filtrate with water 3 times, dried to obtain asparagus extract.

[0024] In this embodiment, both boiling w...

Embodiment 3

[0028] On the basis of Example 1, the obtained asparagus extract was subjected to silica gel column chromatography, eluted with a mixture of chloroform and methanol, and the eluate of the asparagus extract was collected, concentrated in vacuo at 37° C., and the asparagus extract was obtained again. Wherein, in the mixed solution, the volume ratio of chloroform to methanol is 7:3.

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Abstract

The invention discloses a preparation method of an asparagus extract. The preparation method comprises the following steps that boiling water is added to dried asparagus powder, the liquor ratio is 1:16 to 1:19, boiling water extraction is performed for 2.1-2.4 hours, and filtration is performed to obtain an extracting solution; the extracting solution is subjected to standing for 12-16 hours, suction filtration is performed, the filter substance is dried to obtain a crude asparagus extract product; boiling water and saturated lime water are added into the crude asparagus extract product, a pH value is regulated to be 7-8,the liquid is kept in a boiling state till the crude asparagus extract product is completely dissolved, and filtration is performed to obtain filtrate, wherein the proportion of the crude asparagus extract product to the boiling water to the saturated lime water is 1 to 90-100 to 25-33; a hydrochloric acid solution is utilized to regulate the pH value of the filtrate to be 4.1-4.9, standing is performed for 50-70 minutes, suction filtration is performed, a suction filtration substance is washed with water for 2-4 times, and drying is performed to obtain the asparagus extract. The invention further the asparagus extract and application of the asparagus extract. The asparagus extract is used for treating cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to an asparagus extract and a preparation method and application thereof. Background technique [0002] Asparagus, also known as Shi Diaobo, is a perennial herb of the genus Asparagus. Its stems are divided into underground rhizomes, bulbs, and aboveground stems. The aboveground stems are fleshy stems, which are product organs. Asparagus can be used not only as a health product, but also in cosmetics, and can also be used as a therapeutic drug for cardiovascular and cerebrovascular diseases. For the treatment of cardiovascular and cerebrovascular diseases, specifically, it can maintain the normal osmotic pressure of blood vessels and reduce the fragility of blood vessels. [0003] Cardiovascular and cerebrovascular disease is a general term for cardiovascular and cerebrovascular diseases, and is the manifestation of systemic vascular disease or systemic vascular disease in the heart and ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P9/10
CPCA61K36/899A61K2236/331
Inventor 龙日荣
Owner 广州市天河华南发展有限公司
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