Simulated oral cavity device for collecting buccal cigarette dissolved matter and using method thereof

Abstract

The invention relates to the technical field of simulated oral cavity devices and relates to a simulated oral cavity device for collecting buccal cigarette dissolved matter and a using method thereof. The simulated oral cavity device dissolves out and collects matter in buccal cigarettes in a simulated buccal state and comprises two layers of thin films, a constant-temperature water bath and a guide-out end capillary tube, edges around the thin films are in press-fit airtight to form a film wrapping jacket, an interlayer for placement of a buccal cigarette sample is arranged between the thin films, and infiltration liquid is guided into the interlayer by adopting a method of membrane permeation or capillary tube diversion to infiltrate the buccal sample; the film wrapping jacket is put below liquid level of liquid in the constant-temperature water bath, and one end of the guide-out end capillary tube extends into the interlayer while the other end of the same is connected with a dissolved liquid collection component. The simulated oral cavity device enables contact area of the buccal sample and the thin films to be consistent with that in a real oral cavity; during an experiment, the buccal sample is in a temperature environment in a simulated oral cavity, and pressure of the liquid can simulate pressure between gingiva and cheek.

Description

technical field [0001] The invention relates to the technical field of simulated oral cavity devices, in particular to a simulated oral cavity device for collecting snus extracts and a method for using the same. Background technique [0002] Chinese invention patent "Device and Simulation Method for Simulating Mouth Dissolution of Smokeless Tobacco Products", publication number: 104198662A, the device includes a constant temperature water bath box, a dual-channel peristaltic pump, and a collection bottle, all of which are placed in the constant temperature water bath box The artificial saliva and the artificial oral cavity device in the artificial oral cavity device are provided with a dissolution vessel for placing the oral-type smokeless tobacco product and containing the liquid. The liquid dissolution core unit used as a mouth-type smokeless tobacco product is an open container. Although the container is placed in a constant temperature water bath, the smokeless tobacco p...

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Problems solved by technology

The liquid dissolution core unit used as a mouth-type smokeless tobacco product is an open container. Although the container is placed in a constant temperature water bath, the smokeless tobacco product is still exposed to the air, which is not conducive to heat preservation; although the device adopts peristaltic The pump inputs artificial saliva, but the method of dripping the solution on the sample of smokeless tobacco products is adopted. In this method, only when there is enough solution absorbed in the sample, excess solution will drip from the bottom of the sample, which will exceed the oral cavity. The amount of solution infiltration of smokeless tobacco products in the real oral environment, and, with the different raw materials and specifications of products, the solution relies on natural infiltration, and the amount of solution infiltrated by it is not controlled, resulting in the extraction of dissolved substances in the solution. The concentration in different samples is different, and the method is not easy to grasp the comparability of the test data of different samples; in addition, the artificial oral cavity device is a metal container (210) consistent with the volume of the oral cavity, and when the mouth-type smokeless tobacco product is actually used, It is located between the gums and cheeks in the mouth, adheres to the mucous membrane, and occupies the volume enclosed by the cigarette pouch or the surface of the product itself

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