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Traditional Chinese medicine compound for preventing and controlling vibriosis, as well as preparation method and application thereof

A composition and technology for vibrosis, applied in the directions of antibacterial drugs, pharmaceutical formulations, plant raw materials, etc., can solve the problems of unreasonable dosing, unsatisfactory bacteriostatic effect, and exaggerated product efficacy, etc., to enhance immunity of the body. The effect of strength, resistance to drug resistance, and low cost

Inactive Publication Date: 2017-07-07
广州市普精生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The antibacterial Chinese patent medicines for aquatic products in the market have unsatisfactory antibacterial effects. The main reasons are that the prescriptions are random, the processing is rough, the method of administration is unreasonable, and the efficacy of the products is exaggerated.

Method used

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  • Traditional Chinese medicine compound for preventing and controlling vibriosis, as well as preparation method and application thereof
  • Traditional Chinese medicine compound for preventing and controlling vibriosis, as well as preparation method and application thereof
  • Traditional Chinese medicine compound for preventing and controlling vibriosis, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A traditional Chinese medicine composition for preventing and treating vibriosis, which is prepared from loropetalum leaves, lobelia, astragalus, glucose, and minerals according to the following proportions by weight:

[0035]

[0036] The preparation method of composition of the present invention is described in detail below:

[0037] S1. Mix loropetalum leaves and Lobelia, extract twice with water of 12 times the weight of medicinal materials, and filter for 1.5 hours each time; combine the filtrates, concentrate under reduced pressure at 65°C to form the first thick paste, and mix the first thick paste with The weight ratio of medicinal materials is 1:1; under rapid stirring, add ethanol to the first thick ointment to make the alcohol content 70%, let it stand overnight, take the supernatant and filter, and the filtrate is recovered under reduced pressure at 65°C for ethanol, concentrated Become the second thick ointment, the weight ratio of the second thick ointm...

Embodiment 2

[0041] A traditional Chinese medicine composition for preventing and treating vibriosis, which is prepared from lobelia flower, loropetalum leaf, vitex flower, coptis leaf, fish meal, crude protein, soybean meal, and flour according to the following proportions by weight:

[0042]

[0043] The preparation method of composition of the present invention is described in detail below:

[0044]S1. Mix loropetalum leaves and lotus lobelia, extract twice with water of 8 to 18 times the weight of medicinal materials, and filter for 1 hour each time; combine the filtrates, concentrate under reduced pressure at 80°C to form the first thick paste, the first thick The weight ratio of ointment to medicinal raw materials is 1.2:1; add ethanol to the first thick ointment under rapid stirring, so that the volume content of ethanol is 60%, let it stand overnight, take the supernatant and filter, and the filtrate is recovered under reduced pressure at 80°C Ethanol, concentrated into the seco...

Embodiment 3

[0048] A traditional Chinese medicine composition for preventing and treating vibriosis, which is prepared by the following proportions by weight:

[0049]

[0050] The preparation method of composition of the present invention is described in detail below:

[0051] S1. Mix loropetalum leaves and lobelia, extract twice with water of 18 times the weight of the raw materials of medicinal materials, and filter for 1 hour each time; combine the filtrates, concentrate under reduced pressure at 50-80°C to form the first thick paste, the first thick The weight ratio of the ointment to the raw material of medicinal materials is 1.2:1; under rapid stirring, add ethanol to the first thick ointment to make the ethanol volume content 60%, let it stand overnight, take the supernatant and filter, and the filtrate is reduced at 50-80°C. Pressure recovery ethanol, concentrated into the second thick ointment, the weight ratio of the second thick ointment and medicinal raw materials is 1.5:3...

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Abstract

The invention relates to a traditional Chinese medicine compound for preventing and controlling vibriosis, as well as a preparation method and application thereof. The traditional Chinese medicine compound comprises the following effective constituents in parts by weight: 200-300 parts of Chinese lobelia, 400-500 parts of loropetalum leaves and 200-500 parts of X, wherein X is one or more of astragalus membranaceus, agnuside, elephantopus scaber flowers, coptis chinensis leaves and scutellaria baicalensis. The Chinese herbal medicines, such as, loropetalum leaves and Chinese lobelia, are used as the effective constituents of the compound provided by the invention; the effect for preventing and controlling vibriosis is excellent; the toxic side effect is small, no residue exists and the pathogene is difficult to generate drug resistance; the compound provided by the invention is wide in raw material source, is low in cost, can be prepared into various preparations and is more flexibly applied; the compound for preventing and controlling vibriosis provided by the invention has the functions of resisting against vibriosis, resisting against protozoon and enhancing immunity of the organism, can be prepared into the drug for preventing and controlling vibriosis and has a popularization value.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition for preventing and treating vibriosis and its preparation method and application. Background technique [0002] Vibriosis is one of the most common problems in the process of prawn farming. No matter in the past or now, it is considered to be one of the important reasons hindering the development of prawn farming at home and abroad. At present, there is still a lack of ideal drugs. [0003] my country's prawn farming industry has created brilliant achievements and has become one of the industries with the best economic benefits, making important contributions to the prosperity of the coastal economy and the enrichment of domestic and foreign markets. According to the estimates of the Food and Agriculture Organization of the United Nations (FAO), the overexploitation of the offshore fish and shrimp industry has led to a decline in catches. By ...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61P31/04
CPCA61K36/185A61K36/28A61K36/34A61K36/481A61K36/515A61K36/539A61K36/718A61K36/85A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 朱盛山
Owner 广州市普精生物科技有限公司
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