Oscillating flow micromixer

Abstract

The invention discloses an oscillating flow micromixer which comprises an oscillator, an inlet channel, circular chambers, connecting channels and an outlet channel; the oscillator, the inlet channel, the circular chambers, the connecting channels and the outlet channel are positioned in the same one plane; the oscillator is arranged at the inlet channel; a first inlet channel is tangentially connected with the first circular chamber, the first connecting channel is tangential to the first circular chamber and the second circular chamber, and the position of the first connecting channel is positioned at the position close to the oscillator; the remaining connecting channels are sequentially tangential to the excircles of the two circular chambers which are connected, and the remaining connecting channels are perpendicular to the front connecting channel and are positioned between the connected circular chambers and the front circular chamber; the outlet channel is tangential to the excircle of the last circular chamber, is perpendicular to the cth connecting channel and positioned between the last two circular chambers. The micromixer is applicable to mixing of high-flow fluid with wide viscosity range, and has better universality.

Description

technical field [0001] The invention belongs to microfluidic devices, in particular to an oscillating flow micromixer. Background technique [0002] Microfluidics is an interdisciplinary science and technology involving precision machinery, fluid mechanics, biomedicine, chemistry, etc. It is widely used in biochemical analysis, medical diagnosis, drug screening, etc., and has high efficiency and required Due to the advantages of fewer samples / reagents and convenient miniaturization of instruments and equipment, it has achieved rapid development in recent years. Microfluidic mixing enhancement is a key issue in the research of microfluidic technology. At low scales, the inertial forces of the liquid weaken and the viscous forces gradually increase, making mixing difficult, while at the same time, when the liquid is highly viscous, mixing becomes more difficult. Common micromixer designs are divided into two types: active and passive. [0003] Active mixing uses external fo...

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Problems solved by technology

(A.Alam, K.Y.Kim, Mixing performance of a planar micromixer with circular chambers and crossing constriction channels, Sensor Actuat B-Chem, 176 (2013) 639-652.) But the mixing effect of this structure will weaken as the viscosity increases, That is, the Reynolds number Re<50, the mixing effect is significantly reduced

[0006] In addition, the use of oscillating flow can also improve fluid mixing (H.M.Xia, Z.P.Wang, W.Fan, A.Wijaya, W.Wang, Z.F.Wang, Converting steady laminar flow to oscillatory flowthrough a hydroelasticity approach at microscales, Lab Chip , 12(2012) 60-64; H.M.Xia, Z.P.Wang, V.B.Nguyen, S.H.Ng, W.Wang, F.Y.Leong, D.V.Le, Analyzing the transition pressure and viscosity limit of a hydroelastic microfluidicoscillator, ApplPhysLett, 104(2014)), Xia et al. reported an oscillator that does not need an external excitation source. It can oscillate spontaneously only under certain pressure conditions and is used for liquid mixing. The oscillator is applied to a Y-shaped structure channel and can work passively. However, there is a problem in the application of this kind of mixer on the Y-shaped structure channel. At a fixed oscillation frequency, when the fluid flow rate is high, it is easy to form a long liquid segment inside the flow channel, and the liquid contacts The smaller the area, the lower the mixing effect

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