Retaining structure and detector comprising retaining structure

Abstract

The invention relates to a retaining structure for retaining a sample detection porous plate. The porous plate is provided with an electrode and accommodates a sample. The retaining structure comprises a retainer and a pressure conversion plate. The retainer comprises a retainer main body and at least one probe module, wherein the retainer main body has an accommodating part for receiving the porous plate, and the probe module is arranged at the bottom of the accommodating part. The probe module comprises a plurality of contact probes, at least one switch probe and an electric insulating plate, wherein one end of each contact probe comprises an elastic contact terminal translating in a direction perpendicular to the bottom of the accommodating part, and the other end of each contact probe is electrically connected with a retainer control circuit; one end of each switch probe comprises an elastic pressing part translating in a direction perpendicular to the bottom of the accommodating part, and the other end of each switch probe is electrically connected with the retainer control circuit; and the contact probe and the switch probe are arranged on the electric insulating plate in a penetrating manner. When the porous plate is received in the accommodating part, the bottom of the porous plate presses against the elastic contact terminal of the contact probe and the elastic pressing part of the switch probe, the elastic contact terminal is electrically connected with the electrode arranged on the bottom of the porous plate, and the porous plate is disposed between the pressure conversion plate and the bottom of the accommodating part.

Description

Technical field [0001] The invention relates to a holding structure for holding a sample detection orifice plate, and to a detector including the holding structure. Background technique [0002] In the field of sample detection, especially in the field of liquid biopsy detection, a well plate with multiple holes is usually used to hold biological samples. The electrodes of the well plate are electrically connected to the bottom of the holes, so the weak current signal of the biological sample The electrode can be output to the signal detection processing unit outside the orifice plate. In addition, because the concentration of the captured target molecules is very low, the current signal that can be detected is also very weak, usually on the order of nanoamperes or picoamps. In the existing detection equipment, generally only the milliamp level can be detected. Therefore, there is a need for a holding structure that can repeatedly place the orifice plate and prevent the orifice...

AI Technical Summary

Problems solved by technology

In addition, because the concentration of the captured target molecule is very low, the current signal that can be detected is also very weak, usually on the order of nanoampere or picoampere

However, in the existing detection equipment, generally only the detection of milliampere level can be achieved.

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