Empathy nerve experiment system based on observational fear acquisition

Abstract

The invention provides an empathy nerve experiment system based on observational fear acquisition. The empathy nerve experiment system based on observational fear acquisition comprises a behavioristics implementation device, a video monitoring device, a physiological signal acquisition device, a light control device and an electric signal acquisition device. The behavioristics implementation device comprises an observational fear acquisition experiment box, and a victim mouse and an observer mouse are put in the observational fear acquisition experiment box in the experiment process. The observational fear acquisition experiment box is used for carrying out an electric shock on the victim mouse. The light control device is used for carrying out specific neuron irradiation on a target region of brain tissue of the victim mouse. The video monitoring device is used for acquiring behavior reactions of the observer mouse. The physiological signal acquisition device is used for acquiring physiological reactions of the observer mouse. The electric signal acquisition device is used for acquiring activity signals of the observer mouse. The empathy nerve experiment system can be used for evaluating the emotional empathy states of animals and exploring relevant neural circuit mechanisms in combination with optogenetics.

Description

technical field [0001] The present invention relates to the technical field of ethology, in particular to the research equipment of ethology, specifically an empathic nerve experimental system based on observational fear acquisition. Background technique [0002] Emotion is an important product of brain activity. Among the six basic emotions, fear is considered to be of great significance to the survival of mice. A series of psychological and physiological responses that mice show in the face of danger can help mice quickly escape from adverse conditions. environment. And fear not only comes from personal experience, but also through the emotions and behaviors of others. This process is called indirect emotional infection, also called empathy. However, there is another phenomenon in mice that can also copy the behavior of peers. This phenomenon is called imitation. It is difficult to distinguish empathy from imitation in terms of behavioral performance. Therefore, general ...

AI Technical Summary

Problems solved by technology

[0008] Glacial acetic acid injection, as an existing embodiment of indirect emotion acquisition, is too harmful to experimental mice, and the damage cannot be quantified and difficult to control, often causing accidental death of mice, and the recovery of this stimulation is very poor , too much trauma for experimental mice

[0009] Existing implementation schemes cannot perform real-time neuron regulation and neuron activity signal detection, and even if there are, they are all independent systems, and it is impossible to form an integrated exploration scheme

[0010] There is no multi-faceted indicator in the existing technology to judge whether it is empathy or simple behavioral imitation, because the existing technology only obtains the data of mouse behavior through video and analyzes the behavior to obtain the emotional state of the mouse. The behavioral response can only be used as one aspect of the emotional state, and it needs to be judged together with the physiological state. The heartbeat of the mouse will change in the state of fear and anxiety, so the detection of physiological indicators is added. Combining with the behavioral phenomenon Emotional state of the mouse

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