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Pharmaceutical composition for improving female climacteric insomnia and preparing method and application thereof

The technology of a composition and a medicine is applied in the field of a pharmaceutical composition for improving female menopausal insomnia and the preparation field thereof, which can solve the problems of high cost and complex composition, and achieve the effects of low cost, simple composition and improving female menopausal insomnia.

Active Publication Date: 2016-08-17
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned composition has disadvantages such as complex composition and high cost, which limit its application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The raw materials of the pharmaceutical composition for improving female climacteric insomnia in this example are as follows: Rehmannia glutinosa 4g, Achyranthes bidentata 3g, Cornus officinalis 3g, Semen jujube 3g, Cortex Albiziae 2g, Cortex Moutan 2g;

[0039] The preparation method of the pharmaceutical composition comprises the following steps: taking selected weights of Rehmannia glutinosa, Achyranthes bidentata, Cornus officinalis, jujube seed, Albizia jubis cortex and Moutan cortex, heating and refluxing to extract twice, and adding 8 weight times of Water extraction for 2 hours, the second time adding 6 times the weight of water for extraction for 2 hours, combining the extracts, filtering, and concentrating the filtrate to a relative density of 1.15-1.25 at 80°C to obtain the product.

[0040] In this example, the pharmaceutical composition for improving female climacteric insomnia is prepared into granules by adding conventional auxiliary materials and followin...

Embodiment 2

[0042] The raw materials of the pharmaceutical composition for improving female climacteric insomnia in this example are as follows: Rehmannia glutinosa 4g, Achyranthes bidentata 4g, Cornus officinalis 4g, Suanzaoren 3g, Cortex Albizia Julibrissin 2g, Cortex Moutan 2g;

[0043] The preparation method of the pharmaceutical composition comprises the following steps: taking selected weights of Rehmannia glutinosa, Achyranthes bidentata, Cornus officinalis, jujube seed, Albizia jubis cortex and Moutan cortex, heating and refluxing to extract twice, and adding 8 weight times of Water extraction for 2 hours, the second time adding 6 times the weight of water for extraction for 2 hours, combining the extracts, filtering, and concentrating the filtrate to a relative density of 1.15-1.25 at 80°C to obtain the product.

[0044] In this example, the pharmaceutical composition for improving climacteric insomnia in females is prepared into tablets by adding conventional excipients and follo...

Embodiment 3

[0046] The raw materials of the medicinal composition for improving insomnia in females in this embodiment are as follows: Rehmannia glutinosa 3g, Achyranthes bidentata 6g, Cornus officinalis 3g, Semen jujube 5g, Cortex Albizia Julibrissin 1g, Cortex Moutan 3g;

[0047] The preparation method of the pharmaceutical composition comprises the following steps: taking selected weights of Rehmannia glutinosa, Achyranthes bidentata, Cornus officinalis, jujube seed, Albizia jubis cortex and Moutan cortex, heating and refluxing to extract twice, and adding 8 weight times of Water extraction for 2 hours, the second time adding 6 times the weight of water for extraction for 2 hours, combining the extracts, filtering, and concentrating the filtrate to a relative density of 1.15-1.25 at 80°C to obtain the product.

[0048] In this example, the pharmaceutical composition for improving female climacteric insomnia is made into capsules by adding conventional auxiliary materials and following con...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for improving female climacteric insomnia and a preparing method and application thereof. The pharmaceutical composition comprises, by weight, 1-9 parts of prepared rehmannia roots, 1-9 parts of radix achyranthis bidentatae, 1-9 parts of dogwood, 1-6 parts of spina date seeds, 1-6 parts of silktree albizzia bark and 1-6 parts of moutan bark. The disease cause of female climacteric insomnia is analyzed according to the theory of traditional Chinese medicine, prepared rehmannia roots, radix achyranthis bidentatae, dogwood, spina date seeds, silktree albizzia bark and moutan bark are selected as raw materials, the ratio of all the raw materials is further optimized and selected, all the raw materials in the pharmaceutical composition are in coordination with each other and jointly act according to the compatibility relationship, the pharmaceutical composition has the effects of nourishing the liver and the kidney, quieting the heart and calming the nerves, and the effect of improving female climacteric insomnia is played accordingly; the pharmaceutical composition only comprises the six raw materials, the composition is simple, and cost is low.

Description

technical field [0001] The invention belongs to the field of medicines or health care products, and in particular relates to a pharmaceutical composition for improving climacteric insomnia, a preparation method and application thereof. Background technique [0002] Menopause refers to the transitional stage of women from reproductive capacity to non-reproductive capacity, which generally occurs between the ages of 45 and 55 in women. At this stage, women experience menstrual changes, such as frequent menstruation, less menstrual flow, irregular menstruation, and amenorrhea. At the same time, due to changes in ovarian endocrine function, menopausal women may experience mild or severe syndromes mainly based on autonomic nerve dysfunction. Insomnia, chest tightness, palpitations, depression, waist pain. Insomnia is one of the most prominent chronic diseases that plague menopausal women. [0003] In recent years, due to the aging population, accelerated pace of life, and incr...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P15/12A61P25/20
CPCA61K36/21A61K36/40A61K36/48A61K36/71A61K36/725A61K36/804A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 王丽菊于娟罗志毅夏裕发林小红
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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