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Nicotine formulations and methods of making the same

A kind of technology of nicotine and preparation, applied in the field of producing dry powder nicotine preparation suitable for inhalation

Inactive Publication Date: 2016-08-03
PHILIP MORRIS PROD SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, each of these techniques suffers from the same result that less than half of the inhaled nicotine and related compounds remain in the lungs, but the remainder is exhaled into the environment
Unfortunately, this means that the public still has to grapple with the same issues that users of these technologies actually produce second-hand smoke, and as a result these technologies are increasingly banned in selected public spaces.

Method used

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  • Nicotine formulations and methods of making the same
  • Nicotine formulations and methods of making the same
  • Nicotine formulations and methods of making the same

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Embodiment Construction

[0013] Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although any methods and materials similar or equivalent to those described herein can be used in the practice or testing of the present invention, the preferred methods and materials are described.

[0014] As used herein, the following terms each have the meaning associated with them in this section.

[0015] The articles "a / an" are used herein to refer to one or more than one of the grammatical object of said article (ie, to refer to "at least one"). By way of example, "an element" means one element or more than one element.

[0016] "About" as used herein, when referring to a measurable value, such as an amount, duration, etc., is meant to encompass ±20% or ±10% deviations, more preferably ±5% deviations, even more preferably ±1% deviations from the specified value deviations, and...

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Abstract

A dry powder nicotine formulation suitable for inhalation is described. The formulation includes nicotine particles, wherein the nicotine particles are substantially in the range of about 1-10 micron in size, preferably 2-5 micron in size. The formulation may also include a cough suppressant component having particles in the 5-100 micron size range. The formulation may also include a cough suppressant component having particles in the 10-200 micron size range. The formulation may also include a flavor component having particles in the 10-1000 micron size range.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US Patent Application Serial No. 61 / 976,712, filed April 8, 2014, which is hereby incorporated by reference in its entirety. Background technique [0003] Cigarette smoke is believed to contain about 4000 chemical compounds and has a particle size range of less than 0.1 micron to about 0.5 micron. During inhalation, most particles known to be larger than 10-12 microns in size typically do not complete a turn in the mouth and enter the lower respiratory tract, but instead impinge on the back of the larynx. While particles smaller than 5 microns in size are generally considered respirable and thus able to enter the lower airways, most particles smaller than 1 micron in size do not settle in the alveoli and are therefore expelled during subsequent exhalation. Thus, exhaled particles in this size range (less than about 1 micron) are often characterized as "secondhand smoke." [0004] Cu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/465A61K9/72
CPCA61K9/0075A61K9/145A61K9/1623A61K31/045A61K31/465A61K45/06A61P11/14A61P25/34A61P43/00Y10T428/2982A24B13/02A24B15/16A24D1/18
Inventor 亚历克斯·斯藤兹勒亚瑟·斯卢茨基诺埃·扎迈勒
Owner PHILIP MORRIS PROD SA
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