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Traditional Chinese medicine spray for treating rhinitis and preparation method thereof

The technology of a spray and a traditional Chinese medicine is applied in the field of traditional Chinese medicine spray for treating rhinitis and its preparation, which can solve the problems of easy outflow, small mucosal contact area, unfavorable drug efficacy, etc. itching effect

Inactive Publication Date: 2016-05-11
TAISHAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although nasal drops are administered through the nasal cavity, they have a small contact area with the mucous membrane and are easy to flow out, which is not conducive to the efficacy of the drug.

Method used

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  • Traditional Chinese medicine spray for treating rhinitis and preparation method thereof
  • Traditional Chinese medicine spray for treating rhinitis and preparation method thereof
  • Traditional Chinese medicine spray for treating rhinitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031](1) Xanthium 306g, Scutellaria baicalensis 225g, Goose Bubivora 160g, Asarum 56g, Catechin 108g, Astragalus 270g, Borneol 2g, Water-soluble Chitosan 2g, Chlorhexidine Acetate 1.2g and Tween-8010g, Water for injection up to 1000mL;

[0032] (2) Take 306g of processed cocklebur, 160g of goose herbivore and 56g of asarum according to the weight of claim 1, add 6 times the amount of water, soak for 2 hours, steam distill for 3 hours to extract volatile oil, and set aside. Take 225g of Scutellaria baicalensis and 270g of Astragalus membranaceus, add 10 times the amount of water for the first time, soak for 2 hours, and decoct for 2 hours; add 8 times the amount of water for the second time, and decoct for 1 hour. The decoction liquids were combined, filtered, and concentrated into a clear paste with a relative density of 1.20 at 60°C. Add 95% ethanol until the alcohol content reaches 70%, let it stand, filter, recover ethanol under reduced pressure, and use the obtained medi...

Embodiment 2

[0034] (1) Xanthium 330g, Scutellaria baicalensis 210g, Goose Bubivora 150g, Asarum 45g, Catechin 120g, Astragalus 270g, Borneol 3g, Water-soluble chitosan 1.5g, Chlorhexidine acetate 1.2g and Tween-8012g , water for injection up to 1000mL;

[0035] (2) Take 330g of processed cocklebur, 150g of goose herbivore and 45g of asarum according to the weight of claim 1, add 6 times the amount of water, soak for 2 hours, steam distill for 3 hours to extract volatile oil, and set aside. Take 210g of Scutellaria baicalensis and 270g of Astragalus membranaceus, add 10 times the amount of water for the first time, soak for 2 hours, and decoct for 2 hours; add 8 times the amount of water for the second time, and decoct for 1 hour. The decoction liquids were combined, filtered, and concentrated into a clear paste with a relative density of 1.20 at 60°C. Add 95% ethanol until the alcohol content reaches 70%, let it stand, filter, recover ethanol under reduced pressure, and use the obtained ...

Embodiment 3

[0037] (1) Xanthium 270g, Scutellaria baicalensis 252g, Goose Bubivora 180g, Asarum 60g, Catechin 126g, Astragalus 297g, Borneol 3g, Water-soluble chitosan 2.7g, Chlorhexidine acetate 1.5g and Tween-8018g , water for injection up to 1000mL;

[0038] (2) Take 270g of processed cocklebur, 180g of goose herbivore and 60g of asarum according to the weight of claim 1, add 6 times the amount of water, soak for 2 hours, steam distill for 3 hours to extract volatile oil, and set aside. Take 252g of Scutellaria baicalensis and 297g of Astragalus membranaceus, add 10 times the amount of water for the first time, soak for 2 hours, and decoct for 2 hours; add 8 times the amount of water for the second time, and decoct for 1 hour. The decoction liquids were combined, filtered, and concentrated into a clear paste with a relative density of 1.20 at 60°C. Add 95% ethanol until the alcohol content reaches 70%, let it stand, filter, recover ethanol under reduced pressure, and use the obtained ...

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Abstract

The invention discloses a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof. Every 1000mL of the spray is prepared from the following traditional Chinese medicinal materials: 300-400g of prepared fructus xanthii, 200-400g of scutellaria baicalensis, 100-300g of centipeda minima, 30-100g of asarum, 100-200g of catechu, 100-300g of astragalus membranaceus and 1-15g of borneol. In the spray, fructus xanthii and asarum have the effects of promoting the restoration of consciousness, and dispelling to ascend, descend and smooth lung-qi; borneol has the effects of assisting consciousness restoration and dissipation; scutellaria baicalensis has the effects of clearing lung-heat; catechu and centipeda minima with fructus xanthii have the effects of dispersing lung-qi and regulating ascending and descending; astragalus membranaceus has the effects of tonifying qi and solidifying exterior, healing sore and promoting tissue regeneration, so that the curative effects of the medicinal materials are strong. The traditional Chinese medicine spray has the advantages that fructus xanthii, asarum and borneol can be used for promoting restoration of consciousness and relieving symptoms, fructus xanthii and scutellaria baicalensis are used for sterilizing, and astragalus membranaceus is used for repairing injured nasal mucosa and improving immunity, so that the effects of eliminating pathogen, strengthening vital qi and treating both symptoms and root causes can be achieved. Furthermore, the spray also comprises a solubilizer, a preservative and a thickening agent, is convenient to use, can directly reach the acting position, and has high dispersion degree to improve the curative effect. The spray can be used for treating chronic rhinitis, allergic rhinitis and acute rhinitis, and especially has a remarkable curative effect for chronic rhinitis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to pharmaceutical dosage forms, preparation techniques and applications thereof, in particular to a traditional Chinese medicine spray for treating rhinitis and a preparation method thereof. Background technique [0002] The invention relates to a formula and a preparation process of a traditional Chinese medicine spray for treating rhinitis. [0003] Rhinitis, also known as rhinitis, is divided into deficiency and excess in clinical syndrome differentiation in traditional Chinese medicine. The etiology is nothing more than the three evils of wind, dampness, and heat. No matter exogenous or internal injury, fever is the main symptom. In chronic cases, deficiency is contained in excess; rheumatism-heat toxins, following the meridians, gather in the nose, burn the sinus orifices, and cause turbid tears to flow down. Modern research believes that rhinitis is an acu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K9/12A61K47/36A61K47/26A61P11/02A61P37/08A61K31/045A61K31/155
CPCA61K36/28A61K9/0043A61K9/12A61K31/045A61K31/155A61K36/264A61K36/48A61K36/481A61K36/539A61K47/26A61K47/36A61K2236/331A61K2236/39A61K2236/53
Inventor 李菲苏延友刘克
Owner TAISHAN MEDICAL UNIV
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