Noninvasive circulating tumor cell detection and diagnosis device and detection and diagnosis method thereof

Abstract

The invention discloses a noninvasive circulating tumor cell detection and diagnosis device. A high-frequency impulse laser (2), a light beam coupler (4) and an ultrasonic probe (6) are arranged, and the light beam coupler (4) and the ultrasonic probe (6) are both attached to a skin contactor (5). The invention further discloses a detection and diagnosis method of the detection and diagnosis device. According to the technical scheme, on the basis of an in-vivo fluorescence detection method, a photoacoustic effect of biological tissue is combined, and the inaccuracy caused by environmental changes brought by ex-vivo detection is overcome by utilizing photoacoustic specificity of the biological tissue and the deep penetrability of an ultrasonic signal; the effects of clinical detection and noninvasive detection are achieved, blood drawing and marking are not needed, and a novel approach is provided for early detection of clinical tumor cells; the advantages of in-vivo and real-time monitoring are achieved, and detection can be conducted on a patient for a long time; the device is wide in purpose, the equipment structure is simple, operation is convenient, and the safety is high.

Description

technical field [0001] The invention belongs to the technical field of basic medical scientific research and clinical medical testing equipment. More specifically, the present invention relates to a non-invasive detection and diagnosis device for circulating tumor cells. In addition, the present invention also relates to its detection and diagnosis method. Background technique [0002] Cancer is a disease that seriously threatens human health and life. If cancer patients can be detected and treated in time, not only the survival rate can be improved, but also the quality of life of patients can be improved. Therefore, early detection, early diagnosis and timely treatment of cancer are necessary. [0003] In recent years, the early diagnosis of cancer includes imaging diagnosis such as: photoacoustic imaging, photoacoustic tomography, photoacoustic spectral microscopy imaging, etc. The results that can be detected by imaging are often in the middle and late stages of cancer ...

AI Technical Summary

Problems solved by technology

In vivo fluorescent labeling flow cytometry developed in recent years overcomes the problem that imaging detection cannot detect circulating tumor cells in the blood of cancer patients early, and provides a new detection method for early detection of c

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