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A kind of harm reducer and application thereof for selectively reducing NNK in cigarette smoke

A cigarette smoke and selective technology, applied in the fields of application, tobacco, and tobacco treatment, can solve the problems of low chemical activity and NNK difficulty, and achieve the effect of low production cost, easy production and application

Active Publication Date: 2020-02-11
SHANGHAI TOBACCO GRP CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

NNK has a simple molecular structure and low chemical activity, which makes it difficult to reduce NNK in tobacco. In particular, there are few selective harm reduction technologies that only reduce NNK without affecting the taste of cigarettes.

Method used

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  • A kind of harm reducer and application thereof for selectively reducing NNK in cigarette smoke
  • A kind of harm reducer and application thereof for selectively reducing NNK in cigarette smoke
  • A kind of harm reducer and application thereof for selectively reducing NNK in cigarette smoke

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Take 1g cytochrome P450 enzyme, 100g NADPNa by weight 2 , 1200g trisodium citrate, 60g magnesium chloride, add 100kg water to dissolve and make biological enzyme harm reducer. The cytochrome P450 enzyme is selected from any one or a combination of cytochrome P450 isozymes P4501A, P4502A, P4502B, P4502C, P4502D, P4502E, P4503A, P45011A, and P45011B.

[0043] The above-mentioned biological enzyme harm reducer was mixed into the surface material tank, and in the process of adding surface material, it was sprayed on-line on 2027kg tobacco leaf samples by means of compressed air atomization. The amount of the biological enzyme harm reducer applied on the tobacco leaves is 5% of the weight of the tobacco leaves. The reaction time for the biological enzyme harm reducer to be applied to the tobacco leaves is 10 hours. After the reaction, the subsequent processing steps are carried out.

Embodiment 2

[0045] Take 1g cytochrome P450 enzyme, 200g NADPNa by weight 2 , 2400g trisodium citrate, 120g magnesium chloride, add 200kg water to dissolve and make biological enzyme harm reducer. The cytochrome P450 enzyme is selected from any one or a combination of cytochrome P450 isozymes P4501A, P4502A, P4502B, P4502C, P4502D, P4502E, P4503A, P45011A, and P45011B.

[0046]The above-mentioned biological enzyme harm reducer was mixed into the surface material tank, and in the process of adding surface material, it was sprayed on-line on 4054kg tobacco leaf samples by means of compressed air atomization. The amount of the biological enzyme harm reducer applied on the tobacco leaves is 5% of the weight of the tobacco leaves. The reaction time for the biological enzyme harm reducer to be applied to the tobacco leaves is 24 hours. After the reaction, the subsequent processing steps are carried out.

Embodiment 3

[0048] Take 1g cytochrome P450 enzyme, 100g NADPNa by weight 2 , 1200g trisodium citrate, 60g magnesium chloride, add 10kg water to dissolve and make biological enzyme harm reducer. The cytochrome P450 enzyme is selected from any one or a combination of cytochrome P450 isozymes P4501A, P4502A, P4502B, P4502C, P4502D, P4502E, P4503A, P45011A, and P45011B.

[0049] The above-mentioned bio-enzyme harm reducer was mixed into the surface material tank, and in the process of adding surface material, it was sprayed online on 1136kg tobacco leaf samples by means of compressed air atomization. The amount of the biological enzyme harm reducer applied on the tobacco leaves is 1% of the weight of the tobacco leaves. The reaction time for the biological enzyme harm reducer to be applied to the tobacco leaves is 10 hours. After the reaction, the subsequent processing steps are carried out.

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Abstract

The invention provides a harm reducing agent for selectively reducing NNK in cigarette smoke. The harm reducing agent comprises effective ingredients and a proper amount of water. The effective ingredients comprise, by weight, 1 part of biological enzyme, 100-200 parts of NADPNa2, 1200-2400 parts of trisodium citrate and 60-120 parts of magnesium chloride. The invention further provides a preparation and use method for the harm reducing agent for selectively reducing NNK in the cigarette smoke. According to the harm reducing agent for selectively reducing NNK in the cigarette smoke, by the adoption of the biological enzyme harm reducing agent, the NNK content in tobacco leaves can be reduced selectively, the NNK release amount in the cigarette smoke is further reduced, and the harm reducing agent is free of toxicity and harmless, has no adverse effect on the human body and the environment, and is worthy of application and popularization.

Description

technical field [0001] The invention belongs to the technical field of cigarette materials, and relates to a harm reducer for selectively reducing NNK in cigarette smoke and its application, in particular to a biological enzyme harm reducer for selectively reducing NNK in cigarette smoke and its application. Background technique [0002] 4-(Methylnitrosoamino)-l-(3-pyridyl)-1-butanone (NNK), as one of tobacco-specific N-nitrosamines (TSNAs, Tobacco-Specific Nitrosamines), is A strong carcinogenic component unique to tobacco. It is metabolized slowly in the human body, has a long half-life, and is extremely harmful to human health. Therefore, NNK has been included in multiple lists of tobacco harmful ingredients, and it is one of the harmful ingredients in cigarettes that need to be disclosed and reduced. [0003] NNK is mainly formed in the tobacco conditioning stage. Once NNK is formed, it can exist stably in tobacco, and can be transferred to the smoke in large quantitie...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A24B15/20
Inventor 刘兴余周骏朱景溯张杰白若石杨振东易小丽张晨刘冬烨蒋成勇曹伏军
Owner SHANGHAI TOBACCO GRP CO LTD
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