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Pharmaceutical composition for treating angina pectoris and preparation method of pharmaceutical composition

A technology for coronary heart disease angina pectoris and a composition is applied in the field of pharmaceutical compositions for the treatment of coronary heart disease angina pectoris and the field of preparation thereof, which can solve the problems of limited promotion and application of medicinal materials, limited basic research on Altai dogwahua, etc.

Inactive Publication Date: 2015-12-02
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the basic research on Gouba in Altai is still very limited, which limits the subsequent promotion and application of this medicinal material
There are few reports on the chemical constituents and pharmacological effects of Altai Gouba flower in modern research

Method used

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  • Pharmaceutical composition for treating angina pectoris and preparation method of pharmaceutical composition
  • Pharmaceutical composition for treating angina pectoris and preparation method of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: the pharmaceutical composition for the treatment of coronary heart disease angina pectoris and preparation method thereof

[0039] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of coronary heart disease angina pectoris are:

[0040] 260 parts by weight of Altai Gouwa flower, 230 parts by weight of ragwort, 210 parts by weight of Haizhou Changshan bittern A3.5 parts by weight, 0.6 parts by weight of petrogin, 0.2 parts by weight of fritillaria;

[0041] Preparation:

[0042] (1) According to the proportion of raw materials, take Altai Gouba flower and rags, mix them evenly, crush them through a 50-mesh sieve, use ethanol with a concentration of 95% by weight as a solvent, and extract by percolation at 30°C. The extraction times are 3 times. The extraction time is 2 hours each time, and the amount of solvent used each time is 22 times of the total weight of Altai Gouba and Ragbukia medicinal materia...

Embodiment 2

[0045] Embodiment 2: the pharmaceutical composition for the treatment of coronary heart disease angina pectoris and preparation method thereof

[0046] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of coronary heart disease angina pectoris are:

[0047] 250 parts by weight of Altai Gouwa flower, 240 parts by weight of ragwort, 200 parts by weight of Haizhou Changshan Kusu A5, 0.5 part by weight of petrogin, 0.3 part by weight of fritillaria;

[0048] Preparation:

[0049] (1) According to the proportion of raw materials, take Altai Gouba flower and rags, mix them evenly, crush them through a 50-mesh sieve, use ethanol with a concentration of 95% by weight as a solvent, and extract by percolation at 30°C. The extraction times are 3 times. The extraction time is 2 hours each time, and the amount of solvent used each time is 22 times of the total weight of Altai Gouba and Ragbukia medicinal materials to obtain the medici...

Embodiment 3

[0052] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of coronary heart disease angina pectoris

[0053] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of coronary heart disease angina pectoris are:

[0054] 270 parts by weight of Altai Gouwa flower, 220 parts by weight of ragwort, 220 parts by weight of Riposte flower, 220 parts by weight of Haizhou Changshan kusu A2, 0.7 part by weight of petrogin, 0.1 part by weight of fritillaria;

[0055] Preparation:

[0056] (1) According to the proportion of raw materials, take Altai Gouba flower and rags, mix them evenly, crush them through a 50-mesh sieve, use ethanol with a concentration of 95% by weight as a solvent, and extract by percolation at 30°C. The extraction times are 3 times. The extraction time is 2 hours each time, and the amount of solvent used each time is 22 times of the total weight of Altai Gouba and Ragbukia m...

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Abstract

The invention discloses a pharmaceutical composition for treating angina pectoris and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from the following medicinal raw materials in a proportion: heteropappus altaicus, cordia dichotoma fruit, lomatogonium carinthiacum, clerodendrin A, bergenin and peimine. The medicine composition can be prepared according to a conventional preparation process to obtain various preparations, and has a remarkable curative effect on treatment of angina pectoris.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating coronary heart disease angina pectoris and a preparation method thereof. Background technique [0002] Coronary heart disease (Coronary Heart Disease), also known as ischemic heart disease (Ischemic Heart Disease) or coronary heart disease (Coronary Cardiopathy), includes coronary atherosclerosis that narrows and blocks blood vessels and coronary artery spasm, leading to heart disease caused by myocardial ischemia and hypoxia. sick. Angina pectoris (Angina Pectoris) is the most common type of coronary heart disease, which is a clinical syndrome caused by coronary insufficiency, myocardial acute and temporary ischemia and hypoxia. There is no disease name for coronary heart disease in ancient Chinese literature, but similar symptoms have been recorded for a long time. This disease belongs to the categorie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/51A61P9/10A61K31/357A61K31/58A61K31/365
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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