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Composite antioxidant composition and preparation method thereof

An anti-oxidant component and anti-oxidation technology, applied in the directions of drug combination, cosmetic preparations, cosmetics, etc., can solve the problem that the anti-oxidant component cannot have both fullerene function and anti-oxidation function, and achieve good wrinkle removal effect. , Stable antioxidant properties, good whitening effect

Inactive Publication Date: 2015-11-25
PEKING UNIV SHENZHEN GRADUATE SCHOOL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In view of the above deficiencies in the prior art, the object of the present invention is to provide a composite antioxidant composition and its preparation method, aiming to solve the problem that existing antioxidant components cannot have both fullerene and antioxidant functions

Method used

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  • Composite antioxidant composition and preparation method thereof
  • Composite antioxidant composition and preparation method thereof
  • Composite antioxidant composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Weigh 500mgC 60 Powder, 50g PVPk30 powder, 250gL-sodium ascorbate is placed in a ball mill tank, 600 rpm, the refrigeration equipment controls the temperature in the ball mill chamber to 10-15°C (specifically 12°C), after ball milling for 8 hours, the mixed powder is taken out and dissolved in 500ml of deionized water, fully stirred until completely dissolved (stirring time can be 10 minutes, can be placed on a constant temperature magnetic stirrer and stirred with a rotor, the following examples are the same), and then centrifuged (such as 500 rpm, 30 minutes, Following examples are the same), filter to obtain clarified C 60 - Sodium L-ascorbate-PVP complex.

[0043] In this embodiment and the following embodiments, the ball milling mode is selected to run for 15 minutes, stop for 15 minutes, and start and stop the ball milling in a cycle. The ball milling time of each embodiment is calculated according to the actual ball milling time.

Embodiment 2

[0045] Weigh 500mgC 60 Powder, 50g PVPk30 powder, 500gL-sodium ascorbate is placed in a ball mill tank, 600 rpm, the refrigeration equipment controls the temperature in the ball mill chamber to 10-15°C (specifically 10°C), after ball milling for 16 hours, take out the mixed powder and dissolve in 500ml of deionized water, fully stirred until completely dissolved, then centrifuged and filtered to obtain clarified C 60 - Sodium L-ascorbate-PVP complex.

Embodiment 3

[0047] Weigh 500mgC 60 Powder, 50PEG powder, 250gL-sodium ascorbate is placed in a ball mill tank, 400 rpm, the refrigeration equipment controls the temperature in the ball mill chamber to 10-15°C (specifically 15°C), after ball milling for 24 hours, take out the mixed powder and dissolve it in 500ml of deionized water, fully stirred until completely dissolved, then centrifuged and filtered to obtain clarified C 60 - Sodium L-ascorbate-PEG complex.

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Abstract

The invention discloses composite antioxidant composition and a preparation method thereof. The composite antioxidant composition is characterized in that fullerene material is combined with other antioxidant components such as vitamins, carotenes and polyphenols to obtain the composite antioxidant composition with better performance. The composite antioxidant composition has the advantages that the antioxidant action of fullerene can be brought into play while the antioxidant performance of the vitamins, carotenes and polyphenols is stabilized, the composite antioxidant composition has better effects such as better immunity increasing effect, better whitening effect and better wrinkle removing effect in fields such as healthcare and skin caring as compared with the effect of single antioxidant substance.

Description

technical field [0001] The invention relates to the field of fullerene materials, in particular to a composite antioxidant composition and a preparation method thereof. Background technique [0002] In recent years, the term anti-oxidation has been widely concerned, which actually refers to anti-oxidative free radicals. Free radicals refer to atoms or groups with unpaired electrons formed by the homolysis of covalent bonds in the molecules of compounds under external conditions. While the human body inevitably produces free radicals, it also naturally produces antioxidant substances that resist free radicals to counteract the oxidative attacks of free radicals on human cells. Studies have proved that the antioxidant system of the human body is a system with complete and complex functions comparable to the immune system. The stronger the body's antioxidant capacity, the healthier it is and the longer its life. Research on anti-oxidation can effectively overcome the harm it ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/44A61K36/32A61K8/92A61K8/19A61K8/67A61P39/06A61Q19/02A61Q19/08A61K31/375
Inventor 李慧陈恭王春儒居学成
Owner PEKING UNIV SHENZHEN GRADUATE SCHOOL
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