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Active parts of Viola tianshan and its application in the preparation of whitening cosmetics

A technology of Viola tianshanensis and active parts, which is applied in the field of plant extracts and daily chemicals, and can solve the problems of literature and patent reports that have not found the whitening effect of Viola tianshanensis

Active Publication Date: 2018-05-15
王琪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Based on the existing literature, no literature and patent reports have been found that Viola tianshan and its ingredients have whitening effects

Method used

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  • Active parts of Viola tianshan and its application in the preparation of whitening cosmetics
  • Active parts of Viola tianshan and its application in the preparation of whitening cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Take 20 g of dried Viola tianshanensis powder, cold-soak in 200 ml of ethanol with a volume concentration of 30% at room temperature (10-30°C), and extract with ultrasound twice, each time for 10 minutes (500 W). Take the filtrates and combine them, and recover the solvent under reduced pressure to dry, take an appropriate amount of the extract, prepare a 0.5mg / ml solution for later use, and measure its tyrosinase inhibitory effect so as to compare with the activity of the active part of Viola tianshanensis prepared later.

[0018] Result: IC of tyrosinase inhibitory effect of crude extract of Viola tianshanensis 50 It was 2.8 mg / ml.

Embodiment 2

[0019] Example 2 Take 20g of dried Viola tianshanensis powder, cold-soak in 200ml of 60% ethanol at room temperature, and ultrasonically extract twice, each time for 30min (500W), take the filtrates and combine them, recover the solvent under reduced pressure to dryness, and take an appropriate amount of extract , prepared into a 0.5 mg / ml solution for later use, and its tyrosinase inhibitory effect was determined for comparison with the activity of the active part of Viola tianshanensis prepared subsequently.

[0020] Result: IC of tyrosinase inhibitory effect of crude extract of Viola tianshanensis 50 It was 2.9 mg / ml.

Embodiment 3

[0021] Example 3 Take 20g of dried Viola tianshanensis, cold-soak in 200ml of ethanol with a volume concentration of 70% at room temperature, and ultrasonically extract twice, each time for 30min (500W), take the filtrates and combine them, recover the solvent under reduced pressure to dryness, and take an appropriate amount of extract , prepared into a 0.5 mg / ml solution for later use, and its tyrosinase inhibitory effect was determined for comparison with the activity of the active part of Viola tianshanensis prepared subsequently.

[0022] Result: IC of tyrosinase inhibitory effect of crude extract of Viola tianshanensis 50 1.2 mg / ml.

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Abstract

The invention relates to the application of plant extracts in the field of cosmetics with whitening effect, and discloses the application of active parts of Viola tianshanensis in the field of cosmetics with whitening effect. The preparation method of this active part is to take the dry powder of Viola tianshanensis whole plant, extract with ethanol, combine the filtrates, recover the solvent under reduced pressure, and obtain the crude extract of Viola tianshanensis; Extract with n-butanol in sequence, collect, and evaporate to dryness to obtain the active part of Viola tianshanensis. The ethyl acetate and n-butanol fraction of Viola tianshan obtained by the above method is a natural plant extract that has the effect of inhibiting tyrosinase and B16 melanocytes. It has no side effects on the human body and can be used to prepare whitening products. cosmetics.

Description

technical field [0001] The invention relates to the fields of plant extracts and daily chemicals, in particular to the active part of Viola tianshanensis and its application in the preparation of whitening cosmetics. Background technique [0002] In recent years, with the improvement of people's living standards and aesthetic standards, more and more people pursue and yearn for white and clean skin. Therefore, the research and development of whitening cosmetics and skin whitening preparations that can prevent spots and pigmentation caused by sunlight and other reasons are increasingly being paid attention to by cosmetics manufacturers and researchers in various countries. Whitening and antioxidant cosmetics have been Become one of the mainstream varieties of skin care cosmetics. [0003] However, with the frequent occurrence of poisoning incidents of chemically synthesized cosmetics, people began to be keen on plant cosmetics and beauty methods returning to nature. [0004...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q19/02
Inventor 王琪戴沩黎梅
Owner 王琪
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