Wound protecting composition with bleeding-stopping and anti-bacterial functions and preparation method of wound protecting composition
A composition and wound technology, applied in the fields of medical science, bandages, absorbent pads, etc., can solve the problems of failure of anti-adhesion materials, non-healing wounds, slow wound healing, etc. Effect
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Embodiment 1
[0023] Embodiment 1: The preparation method of the wound protection composition with hemostatic and antibacterial function of the present embodiment comprises the following steps:
[0024] Dissolve one or two mixtures of polylactic acid-glycolic acid copolymer and polylactic acid in any organic solvent of DMF, acetone, THF, and hexafluoroisopropanol, and stir at 18°C for 12 hours to prepare mass / volume concentration is 20% organic polymer mixed solution.
[0025] Add one or both of chitosan and chitin to acetic acid, ethanol and water to prepare a 0.5% hemostatic and antibacterial material solution, wherein the volume of acetic acid is 1% of the total solvent volume, and the volume of ethanol and water The ratio is 1:1.
[0026] Inject the organic polymer mixed solution into 5 syringes of the electrospinning equipment respectively, install a No. 5 stainless steel needle, inject the hemostatic and antibacterial material solution into the 3 syringes of the electrospinning eq...
Embodiment 2
[0028] Embodiment 2: The preparation method of the wound protection composition with hemostatic and antibacterial function of the present embodiment comprises the following steps:
[0029] Dissolve one or two mixtures of polylactic acid-glycolic acid copolymer and polylactic acid in any organic solvent such as DMF, acetone, THF, or hexafluoroisopropanol, and stir at 20°C for 12 hours to prepare mass / volume concentration is 30% organic polymer mixed solution.
[0030] Add one or both of chitosan and chitin to acetic acid, ethanol and water to prepare a 5% hemostatic and antibacterial material solution; wherein, the volume of acetic acid is 2% of the total solvent volume, and the volume of ethanol and water The ratio is 1:5.
[0031] Inject the organic polymer mixed solution into 6 syringes of the electrospinning equipment respectively, install a No. 5 stainless steel needle, inject the hemostatic and antibacterial material solution into 4 syringes of the electrospinning equip...
Embodiment 3
[0033] Embodiment 3: the preparation method of the wound protection composition with hemostatic and antibacterial function of the present embodiment, comprises the following steps:
[0034]Dissolve one or two mixtures of polylactic acid-glycolic acid copolymer and polylactic acid in any organic solvent such as DMF, acetone, THF, or hexafluoroisopropanol, and stir at 22°C for 12 hours to prepare mass / volume concentration is the organic polymer mixed solution of 50%.
[0035] One or both of chitosan and chitin are added to acetic acid, ethanol and water to prepare a 10% hemostatic and antibacterial material solution;
[0036] Wherein, the volume of acetic acid is 5% of the total solvent volume, and the volume ratio of ethanol to water is 1:10.
[0037] Inject the organic polymer mixed solution into 8 syringes of the electrospinning equipment respectively, install a No. 5 stainless steel needle, inject the hemostatic and antibacterial material solution into 4 syringes of the el...
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