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Particle classification statistic method and system for scatter diagram and blood cell analyzer

A particle classification and statistical method technology, applied in particle and sedimentation analysis, image analysis, individual particle analysis, etc., can solve the problems of inaccurate classification and inability to solve the individual differences of samples, and achieve the effect of reducing recognition errors and strong stability

Inactive Publication Date: 2015-02-18
SHENZHEN DYMIND BIOTECH
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Problems solved by technology

[0005] The purpose of the present invention is to provide a method and system for particle classification and statistics of scattergrams and a blood cell analyzer, aiming to solve the problem of inaccurate classification caused by the inability of existing methods to solve the problem of individual differences in samples

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  • Particle classification statistic method and system for scatter diagram and blood cell analyzer
  • Particle classification statistic method and system for scatter diagram and blood cell analyzer
  • Particle classification statistic method and system for scatter diagram and blood cell analyzer

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Embodiment Construction

[0061] In order to make the object, technical solution and advantages of the present invention more clear and definite, the present invention will be further described in detail below with reference to the accompanying drawings and examples.

[0062] The scatter diagram particle classification and statistics method provided by the invention, the specific flow chart is as follows figure 2 shown. Include the following steps:

[0063] Step S1: Obtain two-dimensional signals representing different characteristics of particles, and generate a two-dimensional scatter diagram.

[0064] Step S2: Scattergram classification preprocessing, transforming, denoising, and smoothing the generated two-dimensional scattergram, which is beneficial to the subsequent particle classification of the scattergram.

[0065] Step S3: classify the particles in the scatter diagram, and assign a corresponding particle type to each particle in the scatter diagram.

[0066] Step S4: Statistics of particl...

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Abstract

The invention discloses a particle classification statistic method for a scatter diagram, a particle classification statistic system for scatter diagram and a blood cell analyzer. The particle classification statistic method for the scatter diagram comprises the following steps of acquiring two-dimensional signals representing different features of particles, and generating a two-dimensional scatter diagram; pre-classifying the scatter diagram, and performing transformation, noise elimination and smoothing on the generated two-dimensional scatter diagram; classifying scatter diagram particles, and endowing each particle in the scatter diagram with a corresponding particle type; performing scatter diagram particle parameter counting, counting the number of the particles with the same particle type, calculating the percentage of each type of the particles in all the particles, and culling the particles with the interference type to realize classification statistics. According to the particle classification statistic method, features of normal samples can be met, and features of special samples can also be met; therefore, the identification error on the special samples is reduced.

Description

technical field [0001] The invention relates to a method and system for classifying and counting particles of scatter graphs, in particular to a method and system for classifying and counting particles of scatter graphs suitable for blood cell analyzers. Background technique [0002] The main function of the blood cell analyzer is to classify and count the components of human blood cells, especially the classification and counting of white blood cells, which is helpful for doctors to diagnose patients. The five-differentiation blood cell analyzer can divide white blood cells into five categories: lymphocytes, monocytes, neutrophils, basophils and eosinophils. The five-differentiation hematology analyzer is developed on the basis of flow cytometry, which allows white blood cells coated with liquid after reagent treatment to pass through the detection area (flow chamber), and then irradiates laser light on a single cell to collect two Refracted and scattered light at differen...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/14G06T7/00G06F19/00
Inventor 龚文冲
Owner SHENZHEN DYMIND BIOTECH
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