Drug composition for treating neurasthenia and preventing senile dementia
A technology for senile dementia and neurasthenia, applied in the field of biomedicine, can solve problems such as difficult to obtain raw materials and side effects of drugs, and achieve the effect of high drug efficacy, high content of active ingredients, and strong operability
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Embodiment 1
[0034] The pharmaceutical composition for treating neurasthenia and preventing senile dementia consists of the following components in mass percentage:
[0035] Garlic Neural Acid 2%,
[0036] Tofu fruit glycosides 6%,
[0037] Coixenolide 5%,
[0038] Excipients 87%,
[0039] The auxiliary materials are dextrin, lactose, sodium carboxymethyl starch, microcrystalline cellulose, and starch.
[0040] Wherein the garlic fruit nerve acid is extracted and purified according to the following steps:
[0041] (1) Remove the shell and epidermis of the garlic fruit seeds, according to the solid-liquid ratio g / mL of 10:50, mash with phosphate buffer solution with a concentration of 20mM and pH=6.0 at 4°C, and then ultrasonically pulverize 40min, extract overnight at 3°C, then filter with 4 layers of gauze, then centrifuge at 6000 r / min for 40min at 3°C, repeat twice, remove the supernatant to obtain the residue; The salt buffer solution is prepared according to the following operati...
Embodiment 2
[0052] The pharmaceutical composition for treating neurasthenia and preventing senile dementia consists of the following components in mass percentage:
[0053] Garlic Nervous Acid 1%,
[0054] Tofu glucoside 10%,
[0056] Excipients 79%,
[0057] The auxiliary materials are dextrin, lactose, sodium carboxymethyl starch, microcrystalline cellulose, starch, and hydroxypropyl cellulose.
[0058] Wherein the garlic fruit nerve acid is extracted and purified according to the following steps:
[0059] (1) Remove the shell and epidermis of the garlic fruit seeds, according to the solid-to-liquid ratio g / mL of 1:30, mash with phosphate buffer solution with a concentration of 20mM and pH=7.0 at 3°C, and then ultrasonically pulverize 50min, extract overnight at 4°C, then filter with 4 layers of gauze, then centrifuge at 5000r / min at 4°C for 35min, repeat twice, remove the supernatant to obtain the residue; the phosphate buffer The solution is prepar...
Embodiment 3
[0070] The pharmaceutical composition for treating neurasthenia and preventing senile dementia consists of the following components in mass percentage:
[0071] Garlic Nervous Acid 10%,
[0072] Tofu glucoside 1%,
[0073] Coixenolide 1%,
[0074] Excipients 88%,
[0075] The auxiliary materials are dextrin, lactose, sodium carboxymethyl starch, microcrystalline cellulose, starch, and hydroxypropyl cellulose.
[0076] Wherein the garlic fruit nerve acid is extracted and purified according to the following steps:
[0077](1) Remove the shell and epidermis of the garlic fruit seeds, according to the solid-to-liquid ratio g / mL of 8:5, mash with phosphate buffer solution with a concentration of 20mM and pH=7.0 at 4°C, and then ultrasonically pulverize 30min, extract overnight at 4°C, then filter with 4 layers of gauze, then centrifuge at 8000 r / min at 4°C for 30min, repeat twice, remove the supernatant to obtain the residue; The buffer solution is prepared according to the fo...
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