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Traditional Chinese medicine composition with effect of preventing and treating hyperuricemia and preparation method thereof

A technology of hyperuricemia and composition, which is applied in the field of traditional Chinese medicine composition, can solve the problems of strong side effects, etc., and achieve the effect of small side effects, low drug toxicity, and treatment of gout

Active Publication Date: 2014-12-03
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, there are allopurinol and non-steroidal anti-inflammatory drugs for the treatment of gout. The therapeutic effect is good, but the side effects are relatively strong. Patients with heart disease, liver and kidney function, and digestive system dysfunction should strictly follow the doctor's instructions.

Method used

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  • Traditional Chinese medicine composition with effect of preventing and treating hyperuricemia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1 Capsules

[0015] [Prescription] 8 parts by weight of Baifengcai, 6 parts by weight of Ligustrum lucidum, 5 parts by weight of Caulis Spatholobus, and 5 parts by weight of Semen Plantaginis

[0016] 【Preparation method】Dry Baifengcai in the shade, add purified water to extract twice, first add 10 times the amount of purified water and boil for 2 hours, add 8 times the amount of purified water and boil for 1 hour for the second time, filter, and combine the extracts , and concentrated under reduced pressure to a relative density of 1.20 (measured at 80°C), to obtain the extraction paste I; weigh Ligustrum lucidum, Gallis Spatholobus, and Plantaginaceae, add 10 times the amount of purified water to extract twice, each time for 1 hour, filter, and combine The extract was concentrated under reduced pressure to a relative density of 1.15 (measured at 80°C), added ethanol to make the alcohol content of the liquid 60%, stirred, and left to stand overnight, and the s...

Embodiment 2

[0017] Example 2 tablet

[0018] [Prescription] 10 parts by weight of Baifengcai, 8 parts by weight of Ligustrum lucidum, 8 parts by weight of Caulis Spatholobus, 3 parts by weight of Semen Plantaginis

[0019] 【Preparation method】Dry Baifengcai in the shade, add 12 times the amount of purified water to extract by boiling for 2 hours, filter, concentrate under reduced pressure to obtain extract powder Ⅰ; weigh Ligustrum lucidum, Spatholobus, and Plantago, add 12 times the amount Purified water was slightly boiled for 2 hours, filtered, concentrated under reduced pressure to a relative density of 1.20 (measured at 80°C), added ethanol to make the alcohol content of the liquid 50%, stirred, and stood overnight, and the supernatant was concentrated under reduced pressure to relative density. Density is 1.20 (measured at 80°C), and conventional excipients are added and spray-dried to obtain dry extract powder II. Mix dry extract powder Ⅰ and dry extract powder Ⅱ, add convention...

Embodiment 3

[0020] Embodiment 3 oral liquid

[0021] [Prescription] 12 parts by weight of Baifengcai, 4 parts by weight of Ligustrum lucidum, 3 parts by weight of Caulis Spatholobus, 8 parts by weight of Plantago

[0022] [Preparation method] Squeeze the juice of Baifengcai, filter the juice, concentrate under reduced pressure to a relative density of 1.15 (measured at 80°C), and obtain the extraction paste Ⅰ; weigh Ligustrum lucidum, Spatholobus, and Plantago, and add purified water Extract 2 times, first add 10 times the amount of purified water and boil for 2 hours, add 8 times the amount of purified water for 0.5 hours, filter, combine the extracts, and concentrate under reduced pressure to a relative density of 1.18 (80°C test), add ethanol to make the liquid alcohol content to 70%, stir, stand overnight, take the supernatant and concentrate under reduced pressure to a relative density of 1.15 (measured at 80°C), and extract cream II is obtained. Mix extraction ointment I and extr...

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition with an effect of preventing and treating hyperuricemia and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 5-15 parts of gynura formosana, 4-10 parts of fructus ligustri lucidi, 3-10 parts of caulis spatholobi, and 3-10 parts of semen plantaginis. The composition disclosed by the invention combines the medicinal properties of four kinds of medicinal materials which jointly act on organs with gout symptoms, so that the composition effectively treats gout caused by deficiency of liver-yin and kidney-yin; and the composition is low in drug toxicity, and has small side effects on the kidney and the liver.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition capable of preventing and treating hyperuricemia. Background technique [0002] Gout is a metabolic disease caused by increased uric acid synthesis due to abnormal purine metabolism. When renal function is abnormal, the uric acid clearance rate of the kidneys will also increase due to decreased uric acid clearance. Uric acid crystals can affect the feet, most often accumulating in the first metatarsophalangeal joint , resulting in acute inflammatory synovitis. With the continuous improvement of people's living standards, the incidence of gout is increasing year by year, among which the middle-aged and elderly people are a high-incidence group, which seriously affects their quality of life. Currently, there are allopurinol and non-steroidal anti-inflammatory drugs as drugs for the treatment of gout. The therapeutic effect is good, but the side effects are strong. Heart disease patients...

Claims

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Application Information

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IPC IPC(8): A61K36/68A23L1/29A61P19/06A23L33/00
Inventor 刘建顺罗志毅黄婧林小红张栋梁
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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