Sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and preparation method thereof

Abstract

The invention discloses a sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and a preparation method thereof, and relates to a dressing for human body skin wounds. The wound dressing is composed of 1%-1.4% of sodium alginate, 0.6%-1% of sodium carboxymethylcellulose, 0.3%-0.9% of chitosan, 6%-8% of glycerol and the balance of water. The preparation method comprises the following steps: adding sodium alginate and sodium carboxymethylcellulose into water, adding chitosan and acetic acid so as to obtain a uniform solution, and then pouring the uniform solution into a culture dish to perform first freeze drying; then putting the dried material into a CaCl2 solution and an NaOH solution in sequence to soak, performing second freeze drying, soaking in a glycerol aqueous solution, and performing a third freeze drying so as to obtain the product. The preparation technology is simple, the cost is low, the safety and the biocompatibility are better, the characteristics of being high in absorbability, capable of maintaining moist wound condition, low in adhesion, easy to replace and the like are achieved, and wound healing is facilitated.

Description

technical field [0001] The invention relates to a dressing for human surface wounds, in particular to a sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing and a preparation method thereof. Background technique [0002] The skin is an important organ of the human body and plays a protective role for the human body. Skin damage will cause a series of problems in the body, such as bacterial infection, increased metabolism, excessive loss of water and protein, endocrine and immune system dysfunction, etc., which may be life-threatening in severe cases. Therefore, after skin injury, it is usually necessary to use medical dressings to protect the wound, prevent wound infection and severe dehydration, provide a moist environment conducive to wound healing, and promote wound healing. [0003] An ideal medical wound dressing should meet the following conditions: (1) absorb blood and excess exudate without causing fluid accumulation between the dressing and the wou...

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Problems solved by technology

[0009] The purpose of the present invention is to solve the problems that the existing medical dressings cannot keep the wound surface moist, easy to adhere to the wound surface when changing the dressing, short replacement period, poor barrier effect after the dressing penetrates, etc., to provide a medical dressing with easy preparation, high absorbency, high energy Sodium alginate-sodium carboxymethylcellulose-chitosan wound dressing with the advantages of maintaining a moist wound environment, low adhesion, easy replacement, and short nursing cycle and its preparation method

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