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A kind of pharmaceutical composition for treating essential hypertension

A technology of essential hypertension and composition, applied in the field of medicine, which can solve the problems of literature reports that did not find the antihypertensive activity of baogonglin

Inactive Publication Date: 2016-05-18
青岛市市南区人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] By searching the domestic and foreign literature, there is no literature report on the antihypertensive activity of Baotoxin

Method used

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  • A kind of pharmaceutical composition for treating essential hypertension
  • A kind of pharmaceutical composition for treating essential hypertension

Examples

Experimental program
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Embodiment Construction

[0016] The following are specific examples of the present invention, and further describe the technical solution of the present invention, but the protection scope of the present invention is not limited to these examples. All changes or equivalent substitutions that do not depart from the concept of the present invention are included in the protection scope of the present invention.

[0017] Essential hypertensive rats (SHR), clean grade, 180-220g. The rats were randomly divided into the following three groups: the model control group, the positive control group and the patolicin group, with 10 rats in each group, half male and half male. After grouping, they were fed and observed for 3 days for the experiment. Each group was given the corresponding test substance according to the following doses:

[0018] Model control group: equal volume of purified water;

[0019] Positive control group: captopril 10mg / (kg·d);

[0020] Baogonggenalin group: Baogongalin 12mg / (kg·d).

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Abstract

The invention discloses a pharmaceutical composition for treating primary hypertension and an application thereof. The pharmaceutical composition is prepared from an active component and an auxiliary material, wherein the active component comprises baogongteng C. The baogongteng C can not only reduce blood pressure, but also control the blood pressure level smoothly by long-term administration. The invention provides a new candidate medicament for hypertension treatment, and has very important clinical significance.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an antihypertensive drug, in particular to a pharmaceutical composition for treating essential hypertension and its application. Background technique [0002] Essential hypertension (essentialhypertension, ESH) is a common disease. According to the statistics of the Ministry of Health, about 1 / 10 of our country's citizens suffer from hypertension. There are many reasons for this situation, but one of the most important is that the pathogenesis of essential hypertension has not yet been fully understood. At present, the commonly used drugs for the treatment of hypertension are diuretics, sympathetic inhibitors, angiotensin inhibitors, angiotensin converting enzyme inhibitors, calcium ion channel blockers, vasodilators, etc. There are not many applications of pure natural substances in the treatment of hypertension. [0003] Dinggongteng (scientific name: Erycibeobtu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/46A61P9/12
Inventor 殷玉梅
Owner 青岛市市南区人民医院
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