Detection method of aporosa dioica granules

Abstract

The invention relates to a detection method of aporosa dioica granules. The detection method comprises phenotypic traits, identification and detection items, wherein identification comprises the thin-layer identification of menthol, the thin-layer identification of honeysuckle stem, the thin-layer identification of radix bupleuri and the thin-layer identification of bupleurum longiradiatum; as no perfect detection method is developed for detecting active ingredients of the aporosa dioica granules at present, phenomena that related raw materials are not added enough or is not added and fake bupleurum longiradiatum is mixed by illegal manufacturers happen. The detection method is a scientific, reasonable, feasible identification method, the clinical effects of the aporosa dioica granules can be ensured, the medicinal materials have specific quality indexes, the usage of honeysuckle stem, mentha haplocalyx and radix bupleuri in the aporosa dioica granules can be ensured, and therefore, the curative effect of the drug is ensured; besides, the fake bupleurum longiradiatum can be effectively detected, and the harm of radix bupleuri toxins and acetyl radix bupleuri toxins in the bupleurum longiradiatum to the health of patient is avoided.

Description

Technical field: [0001] The invention relates to a detection method of Yinchai particles. Background technique: [0002] Yinchai granule is a variety recorded in the thirteenth volume of traditional Chinese medicine preparations in the "Drug Standards of the Ministry of Health". The standard number is WS3-B-2612-97. It is a granule of pure traditional Chinese medicine. It has the functions of clearing away heat, relieving the surface, and relieving cough. It is clinically used to treat diseases such as wind-heat cold, fever and cough. . But so far, there is no complete set of detection methods for the corresponding detection of its active ingredients, which may lead to unscrupulous manufacturers not strictly following the prescription dosage ingredients in the production of drugs, wantonly reducing high-priced raw materials, resulting in the curative effect of the drug. Significant decline will affect the safety and effectiveness of drugs and seriously damage the interests...

AI Technical Summary

Problems solved by technology

"Shandong Pharmaceutical Industry" published the article "Supplement to the Inspection Method of Bupleurum in the Chinese Pharmacopoeia 2000 Edition" in the fifth issue of the twenty-second volume in 2003. There are obvious deficiencies. It is disclosed in the article that it should be placed for 24 hours, and its detection time is too long, which is not conducive to the control of the drug production process and the supervision and inspection of drug quality; Too little will affect the accuracy of the test; the content of Bupleurum toxin and acetylbupleurum toxin is relatively low, and the observation effect is not good when inspected under ultraviolet light without color development, and the most important thing is the Yinchai granule prescription drug It has many flavors and complex ingredients, and other ingredients will cause confusion and interference. Therefore, it is urgent to find a better way to control the mixing of Bupleurum bupleurum.