Compound composition for treatment of depression

Abstract

The invention discloses a compound composition for treatment of depression and a preparation method thereof. The compound composition takes a novel antidepressant vilazodone hydrochloride and vitamin K as active components. Vitamin K participates in vilazodone hydrochloride to treat severe depression, on the one hand, the clinical dosage of vilazodone hydrochloride can be reduced, a very good antidepressant effect can be generated while maintaining a low dosage, more serious side effects caused by dosage fluctuation similar to gradual dosage increase and gradual dosage decrease during drug withdrawal, and on the other hand, the adverse reaction of abnormal bleeding generated after use of vilazodone hydrochloride can be reduced. Combined use of the two drugs can show stronger antidepressant activity. The compound composition has good application prospects.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, in particular to a compound composition for treating depression, more specifically to a compound tablet composed of vilazodone hydrochloride and vitamin K and a preparation method thereof. Background technique [0002] Depression is a common mental illness. The main clinical manifestations are low mood, loss of interest but not loss, pessimism, slow thinking, lack of initiative, self-blame, poor diet and sleep, and worry that you have various diseases. Illness, I feel discomfort in many parts of the body, and in severe cases, suicidal thoughts and behaviors may appear. According to the statistics of the World Health Organization, the global incidence of depression is about 3.1%, while in developed countries it is close to about 6%. There are 120 million patients with depression worldwide, and it has become the fourth largest disease that threatens human health. With the incre...

AI Technical Summary

Problems solved by technology

This kind of medication method is firstly that the patient’s use plan is relatively cumbersome, and secondly, it is also found in clinical practice that various side effects and adverse reactions are more likely to occur when the dose of vilazodone hydrochloride is changed, and once the depressed patient forgets to increase the dose or suddenly terminates If the drug is used, the expected therapeutic effect will not be achieved or the more dangerous termination symptoms will appear.

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