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Pharmaceutical composition for preventing and treating chicken colibacillosis and preparation method of pharmaceutical composition

A chicken colibacillosis and composition technology, which is applied in the direction of antibacterial drugs, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problem of slowing down of growth rate, loss of chicken farming industry, and affecting the growth and development of chicks. Egg quantity and other issues

Inactive Publication Date: 2014-06-25
HEBEI UNIV OF ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disease can occur in chickens of various ages, manifested as fibrinous pericarditis, fibrinous perihepatitis, enteritis, granuloma, peritonitis, umbilical cord inflammation, salpingitis, ophthalmia and other symptoms, which will seriously affect chicks The growth and development of chickens and the egg production of adult chickens have caused great losses to the chicken industry and restricted the development of my country's chicken industry.
[0003] There are many serotypes of Escherichia coli, and the use of vaccines for prevention and treatment is often ineffective; Western medicine prevention and treatment not only brings about the problem of drug residues, but also promotes the development of drug resistance of bacteria
As the modern chicken industry develops toward scale, standardization, and ecology, the chances of stress factors such as flock transfer and immunity increase greatly. Chickens in a high-production state are highly sensitive to various stress factors, and they are very susceptible to stress when stimulated. Escherichia coli disease occurs, the feed conversion rate decreases, the growth rate slows down or the egg production rate decreases, which affects the efficiency of raising chickens and hinders the development of the chicken industry

Method used

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  • Pharmaceutical composition for preventing and treating chicken colibacillosis and preparation method of pharmaceutical composition
  • Pharmaceutical composition for preventing and treating chicken colibacillosis and preparation method of pharmaceutical composition
  • Pharmaceutical composition for preventing and treating chicken colibacillosis and preparation method of pharmaceutical composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] The preparation of embodiment 1 pharmaceutical composition

[0018] Weigh 3,000 grams of Pulsatilla, 3,000 grams of Coptidis, 3,000 grams of Scutellaria baicalensis, 2,000 grams of Qinpi, 2,000 grams of Andrographis paniculata, 2,000 grams of Radix Radix, 1,500 grams of Curcuma, 1,500 grams of Huoxiang, and 3,000 grams of Licorice, crushed through a 80-mesh sieve, mixed evenly, and kept in a cool place Store in a dry place for later use.

Embodiment 2

[0019] The preparation of embodiment 2 pharmaceutical composition

[0020] Weigh 2,500 grams of Pulsatilla, 2,500 grams of Coptis chinensis, 2,500 grams of Scutellaria baicalensis, 1,500 grams of Qinpi, 1,500 grams of Andrographis paniculata, 1,500 grams of Radix Radix, 1,000 grams of Curcuma, 1,000 grams of Huoxiang, and 2,500 grams of Licorice, crushed through a 80-mesh sieve, mixed evenly, and kept in a cool place Store in a dry place for later use.

Embodiment 3

[0021] Example 3 Prevention of colibacillosis in broiler chickens

[0022] In order to investigate the preventive effect of the pharmaceutical composition of the present invention on broiler colibacillosis, the inventor has carried out animal experiments, specifically as follows:

[0023] experiment method:

[0024] 1.1 Test animals

[0025] Commercially available 1-day-old AA broiler chickens, feeding and management: caged, immunized against Newcastle disease by eye drops and drinking water at 7 and 21 days old; immunized bursa of Fabricius by dripping and drinking water at 10 and 17 days old, respectively.

[0026] 1.2 Grouping and handling of animals

[0027] Seven-day-old AA broilers were randomly divided into two groups, Ⅰ and Ⅱ, with 500 birds in each group. Group II added the medicinal composition of the present invention to the feed at a dose of 0.05% for 14 consecutive days, and Group I was a blank control group.

[0028] 1.3 Experimental design

[0029] At the a...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for preventing and treating chicken colibacillosis and a preparation method of the pharmaceutical composition. The composition comprises the following components in parts by weight: 25-30 parts of Chinese pulsatilla roots, 25-30 parts of coptis chinensis, 25-30 parts of scutellaria baicalensis, 15-20 parts of cortex fraxini, 15-20 parts of common andrographis herbs, 15-20 parts of radix isatidis, 10-15 parts of radix curcumae, 10-15 parts of agastache rugosus and 25-30 parts of liquorice. The composition can be used for effectively inhibiting chicken colibacillosis, increasing the protection rate of broiler chicken not suffering from diseases by 5% and reducing the death rate of laying hens suffering from diseases by 23.4%.

Description

technical field [0001] The invention relates to a pharmaceutical composition for preventing and treating chicken colibacillosis and a preparation method thereof, belonging to the technical field of traditional Chinese medicine and veterinary medicine. Background technique [0002] Chicken colibacillosis is a common conditional disease caused by pathogenic Escherichia coli. The disease can occur in chickens of various ages, manifested as fibrinous pericarditis, fibrinous perihepatitis, enteritis, granuloma, peritonitis, umbilical cord inflammation, salpingitis, ophthalmia and other symptoms, which will seriously affect chicks The growth and development of adult chickens and the egg production of adult chickens have caused great losses to the chicken industry, restricting the development of my country's chicken industry. [0003] There are many serotypes of Escherichia coli, and the use of vaccines for prevention and treatment is often ineffective; Western medicine prevention ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P31/04
Inventor 石玉祥王斌张永英刘彦威杨俊琦钟翠红牛小飞王颂萍索慧娜玄家杰刘月蒋瑞萍马贵达杨九科武振堂
Owner HEBEI UNIV OF ENG
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