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Method for extracting flavone from lithospermum stems and leaves and application thereof in cosmetics

A technology of comfrey flavonoids and cosmetics, which is applied in the direction of cosmetics, cosmetic preparations, toiletry preparations, etc., and can solve the problems of insufficient utilization of comfrey stems and leaves, insufficient extraction and utilization, and high cost of large-scale production. Achieve the effect of creating social and economic value, increasing utilization value and reducing pollution

Active Publication Date: 2014-06-25
松莉美容科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1) At present, in the field of cosmetics, most of the used parts of comfrey are comfrey roots, and the stems and leaves of comfrey containing flavonoids are not fully utilized;
[0006] 2) Comfrey growers can only discard unused comfrey stems and leaves in the field to rot or incinerate, which will cause greater environmental pollution;
[0007] 3) The existing flavonoid extraction methods include water extraction, alkali extraction, and ethanol-petroleum ether extraction methods, and the extraction utilization rate is not thorough enough;
[0008] 4) Most of the alkalis used in the existing extraction methods are sodium hydroxide or sodium carbonate, and the cost of large-scale production is relatively high;
[0009] 5) The acid used in the existing extraction method is hydrochloric acid. Hydrochloric acid is a non-plant acid, which will bring in chloride ions and easily cause skin irritation

Method used

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  • Method for extracting flavone from lithospermum stems and leaves and application thereof in cosmetics
  • Method for extracting flavone from lithospermum stems and leaves and application thereof in cosmetics
  • Method for extracting flavone from lithospermum stems and leaves and application thereof in cosmetics

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Experimental program
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Effect test

Embodiment 1

[0037] Take 500g of cleaned and dried comfrey stems and leaves, mix them and put them into a jacketed pot with a stirrer, then add enough deionized water (the liquid level is not over the solid surface), boil, add lime aqueous solution while stirring , adjust PH=8, reflux under ultrasonic conditions for 60min, suction filter while hot, adjust PH=4 with hydrochloric acid solution to the filtrate under the temperature condition of 60C°, let stand for 2.5h, suction filter, and filter the filtrate twice again, Finally, the three precipitates were combined and washed until neutral, and the crude flavonoids were vacuum-dried at a temperature of 50°C.

Embodiment 2

[0039] Take 500g of cleaned and dried comfrey stems and leaves, mix them and put them into a jacketed pot with a stirrer, then add enough deionized water (the liquid level is not over the solid surface), boil, add lime aqueous solution while stirring , adjust PH=9, reflux under ultrasonic conditions for 45min, suction filter while hot, adjust PH=4 with hydrochloric acid solution to the filtrate under the temperature condition of 60C°, let stand for 2.5h, suction filter, and filter the filtrate twice again, Finally, the three precipitates were combined and washed until neutral, and the crude flavonoids were vacuum-dried at a temperature of 50°C.

Embodiment 3

[0041] Take 500g of cleaned and dried comfrey stems and leaves, mix them and add them to a jacketed pot with a stirrer, then add enough distilled water (the liquid level is not over the solid surface), boil, add lime aqueous solution while stirring, adjust PH=10, reflux for 30min under ultrasonic conditions, suction filtration while hot, adjust PH=4 with hydrochloric acid solution to the filtrate at a temperature of 60C°, let it stand for 2.5h, suction filtration, suction filtration twice again, and finally The three precipitates were combined and washed until neutral, and the crude flavonoids were vacuum-dried at a temperature of 50°C.

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Abstract

The invention relates to a method for extracting flavone from lithospermum stems and leaves and application thereof in cosmetics. The method comprises the following steps: pretreating the lithospermum stems and leaves, and soaking and boiling in water; carrying out alkaline reflux under an ultrasonic condition; carrying out suction filtration and acidic precipitation to obtain lithospermum flavonoids, then applying the obtained lithospermum flavonoids to cosmetics. Therefore, the obtained cosmetics have anti-aging skincare effects.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to the application of a comfrey flavonoid extract extracted from comfrey stems and leaves in cosmetics. Background technique [0002] Comfrey is a perennial herb, usually with 1-3 stems, erect, 40-90 cm high, with appressed and spreading short strigose, with branches on the upper part, and the branches are obliquely ascending and often slightly curved. Leaves sessile, ovate-lanceolate to broadly lanceolate, 3-8 cm long, 7-17 mm wide, apex acuminate, base attenuate, both sides have short strigillose, veins protruding below the leaves, There are dense strigose along the veins. Inflorescence stems and upper parts of branches, 2-6 cm long, prolonged in fruiting stage; bracts are the same shape as leaves but smaller; calyx lobes linear, about 4 mm long, up to 9 mm in fruiting stage, short strigose on the back; corolla white , 7-9 mm long, slightly hairy outside, tube about 4 mm long, eaves nea...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/08A61Q19/00
Inventor 杨广群王小清
Owner 松莉美容科技(上海)有限公司
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