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Medical composite membrane material and preparation method thereof

A composite membrane and medical-grade technology, which is applied in the field of medical composite membrane materials and its preparation, can solve problems such as poor air permeability and moisture permeability, easy scabs, whitening of the skin surface, etc., and achieve improved air permeability, increased channels, and air permeability. The effect of increased humidity

Active Publication Date: 2014-04-30
SHANGHAI BANZAN MACROMOLECULE MATERIAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Currently, the most clinically used dressings are cotton, gauze, etc. Although they are soft in texture, have strong absorption capacity, and have a certain protective effect on the wound surface, they are easy to scab without moisturizing effect, and it is easy to cause wounds when the dressing penetrates. Source infection
However, clinically used bio-derived materials such as pigskin and sheepskin have defects in strength, elasticity, moisture permeability, moisture absorption and drainage, etc., which cannot meet the clinical needs of medicine, and are prone to rejection reactions with the human body, making storage and transportation inconvenient. Limits the large-scale application of such materials
[0005] Polyurethane medical composite membranes have been used in the medical field. Although polyurethane medical composite membranes have certain waterproof and moisture-permeable functions, their air-permeable and moisture-permeable properties are poor. Adhesion to the body surface can easily cause the skin surface to turn white, and patients feel uncomfortable.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Polyurethane A 100

[0026] Acetate starch 30

[0027] Aqueous sodium hydroxide solution: pH 9

[0028] Preparation:

[0029] A1, dissolving polyurethane in N,N-dimethylformyl, making a solid content of 20% polyurethane solution;

[0030] A2, dissolving the acetate starch component in the polyurethane solution to obtain a film-forming liquid;

[0031] A3. Pour a film-forming solution onto one side of the glassine paper substrate, and push it to the other side evenly with a spreader, so that the substrate is covered with a uniform and flat film-forming film solution.

[0032] A4. Put the coated film-forming liquid together with the substrate in an alkaline aqueous solution, take it out after film formation, wash, dry, and peel off from the substrate to obtain a sample film.

[0033]

Embodiment 2

[0041] Polyurethane A 100

[0042] Acetate starch 50

[0043] Aqueous sodium hydroxide solution: pH 9

[0044] Preparation:

[0045] A1, dissolving polyurethane in N,N-dimethylformyl, making a solid content of 20% polyurethane solution;

[0046] A2, dissolving the acetate starch component in the polyurethane solution to obtain a film-forming liquid;

[0047] A3. Pour a film-forming solution onto one side of the glassine paper substrate, and push it to the other side evenly with a spreader, so that the substrate is covered with a uniform and flat film-forming film solution.

[0048] A4. Put the coated film-forming liquid together with the substrate in an alkaline aqueous solution, take it out after film formation, wash, dry, and peel off from the substrate to obtain a sample film.

[0049]

Embodiment 3

[0051] Polyurethane B 100

[0052] Acetate starch 90

[0053] Aqueous sodium hydroxide solution: pH 12

[0054] Preparation:

[0055] A1, dissolving polyurethane in N,N-dimethylformyl, making a solid content of 20% polyurethane solution;

[0056] A2, dissolving the acetate starch component in the polyurethane solution to obtain a film-forming liquid;

[0057] A3. Pour a film-forming solution onto one side of the glassine paper substrate, and push it to the other side evenly with a spreader, so that the substrate is covered with a uniform and flat film-forming film solution.

[0058] A4. Put the coated film-forming liquid together with the substrate in an alkaline aqueous solution, take it out after film formation, wash, dry, and peel off from the substrate to obtain a sample film.

[0059]

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Abstract

The invention discloses a medical composite membrane material which comprises polyurethane and starch acetate. By adopting the starch acetate, the air permeability of the polyurethane composite membrane is improved; on one hand, the starch acetate particles can absorb internal water molecules and are quickly dispersed in the composite membrane under the influence of external air pressure; on the other hand, by adding the starch acetate particles, an alkaline aqueous solution is adsorbed to the surface of the starch acetate particles, the tight and dense structure in the polyurethane matrix is damaged, and the channels of water molecules are increased, so that the air permeability and moisture permeability of a blend membrane are enhanced.

Description

[0001] technical field [0002] The invention relates to the field of medical materials, in particular to a medical composite membrane material and a preparation method thereof. Background technique [0003] The skin is the largest organ of the human body, covering the body surface. It is an important barrier to protect the body from the harm of machinery, chemicals and pathogens, and can prevent the loss of water in the subcutaneous tissue. Use dressings in time to protect the wound, relieve pain, and promote the proliferation and differentiation of skin cells as much as possible to accelerate the healing process. [0004] Currently, the most clinically used dressings are cotton cloth, gauze, etc. Although they are soft in texture, have strong absorption capacity, and have a certain protective effect on the wound surface, they are easy to scab without moisturizing effect, and it is easy to cause wound wounds when the dressing penetrates. source infection. However, clinica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L75/04C08L3/06C08J5/18
Inventor 毕宏海储江顺陈明波程安顺程启山
Owner SHANGHAI BANZAN MACROMOLECULE MATERIAL
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