Automatic analysis instrument and system for microfluidic immunodetection chip

Abstract

The invention discloses an automatic analysis instrument and system for a microfluidic immunodetection chip. The automatic analysis instrument comprises an instrument framework and a mechanical motion module, a liquid moving and sucking module and a detection module which are fixed on the instrument framework, wherein the mechanical motion module comprises a three-dimensional mechanical arm and a metal working pipe fixed on the three-dimensional mechanical arm; the motion of the three-dimensional mechanical arm drives the metal working pipe to move to assemble and disassemble a sucking head; the liquid moving and sucking module is communicated with the metal working pipe and is used for sucking and injecting liquid; the detection module is used for reading and transmitting a chemiluminescence signal on the microfluidic immunodetection chip. The analysis instrument is connected with a computer to form a system and comprehensively realizes organic integration of sample pretreatment, target protein separation purification, sample and reagent injection and suction, chip cleaning and signal acquisition and analysis processing, so that a microfluidic technology is automatic, miniaturized, and more accurate and simple.

Description

technical field [0001] The invention relates to the technical field of microfluidic chip analysis systems, in particular to an automatic analysis instrument and system for microfluidic immune detection chips. Background technique [0002] Microfluidic immunoassay method is a newly developed technology in recent years. This method is mainly based on analytical chemistry, combined with the achievements of related disciplines such as biochemistry, physical chemistry and immunology, and manipulates nanoliter to Fluid in picoliter volume, for immunoreaction detection, has the advantages of small volume, large specific surface area, short reaction time, fast analysis speed, less reagent and sample consumption, and simultaneous detection of multiple samples and multiple indicators. It has important practical value for the discovery of disease markers and early diagnosis of diseases in clinical disease proteomics research. Conventional immunoassays require a relatively long analysi...

AI Technical Summary

Problems solved by technology

[0003] However, in the current microfluidic immunoassay method, in addition to the steps that can be completed on the chip, other operations (such as sample pretreatment, introduction, cleaning, and signal readout detection) mostly need to be done manually, and the steps are cumbersome. The workload is increased, and detection errors are prone to occur, so it cannot be conveniently applied to real-time field detection, and it is not convenient for the wide application and promotion of microfluidic detection methods

Moreover, it cannot fully reflect the advantages of microfluidics, which is essentially high-throughput detection, in this regard.

Images