A capsule for treating senile calcific valvular heart disease and its preparation method

A valvular disease and capsule technology, which is applied in the field of capsules for the treatment of senile calcific valvular heart disease and its preparation, can solve the problems of aggravated stenosis or regurgitation, reduce the incidence of cardiovascular events, etc., achieve convenient treatment, increase liver and kidney burden, The effect of convenience

Active Publication Date: 2015-07-29
烟台力量知识产权服务有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the pathological factor of calcification is not fully considered, it is beneficial to improve the symptoms of heart failure, but it is not helpful to prevent further aggravation of stenosis or insufficiency and reduce the incidence of cardiovascular events

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1, raw material drug weight ratio: 20 parts of persimmon veneer, 10 parts of thorn rose fruit, 6 parts of usnea, 10 parts of citrus aurantium, 6 parts of fragrant structure, 10 parts of equisetum, 10 parts of jelly beans, 10 parts of chrysanthemum 10 copies, 10 copies of August, 2 copies of geckos, 6 copies of Chaifengchai, and 20 copies of Jiaoguya.

[0036] The preparation method of embodiment 1 is: mix persimmon veneer, thorn rose fruit, usnea, citrus aurantium, fragrant structure, equisetum, cassava, shixiangtang, August zha, gecko, firewood, Jiaogu sprout and add water to decoct. After 30 minutes, take the filtrate, add water to the medicinal residue and continue to decoct for 20 minutes, take the filtrate, combine the two filtrates, and divide into two parts for morning and evening use.

Embodiment 2

[0037] Embodiment 2, crude drug weight ratio: 10 parts of persimmon veneer, 6 parts of thorn rose fruit, 3 parts of usnea, 6 parts of turmeric, 3 parts of fragrant texture, 6 parts of equisetum, 6 parts of return cheese, 6 parts of Shixiang 1 serving, 6 servings of August, 1 serving of gecko, 3 servings of Chaifengchai, and 10 servings of Jiaogu sprouts.

Embodiment 3

[0038] Embodiment 3, crude drug weight ratio: 20 parts of persimmon veneer, 10 parts of thorn rose fruit, 6 parts of Usnea, 10 parts of Citrus aurantium, 6 parts of fragrant structure, 10 parts of Equisetum, 10 parts of cheese, 10 parts of Shixiang 10 copies, 10 copies of August, 2 copies of geckos, 6 copies of Chaifengchai, and 20 copies of Jiaoguya.

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PUM

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Abstract

The invention discloses a capsule for treating senile calcific valvular heart disease and a preparation method thereof, so as to solve the problem of cardiac valve calcification is difficult to treat. The preparation method is characterized by comprising the following steps: (1) distilling tetrapanax papyriferum, fruit of rosa davurica pall and littleflower stringbush bark and root through water vapor to extract volatile oil for standby, and storing the decoction dregs for standby; (2) crushing gecko and coked rice sprout into fine powder for standby; (3) uniformly mixing persimmon bark, sunglow, poncirus bark, horsetail, filipendula palmata (pall) maxim, fiveleaf akebia fruit and nakedflower beautyberry branchlet and leaf with the decoction dregs obtained in the step 1, extracting the mixture with alcohol for twice, mixing the two alcohol extracting solutions, filtering, recycling ethanol, and concentrating the filtrate to extract at reduced pressure; (4) adding the fine powder obtained in the step 2 in the extract obtained in the step 3, mixing evenly, drying the mixture at 60 DEG C, crushing the mixture into fine powder, adding polysorbate-80 in the mixture to prepare granules, drying, trimming the granules, spraying the volatile oil obtained in the step 1, mixing evenly, and filling a capsule with the mixture to obtain the capsule. Clinical experiments prove that the capsule for treating senile calcific valvular heart disease disclosed by the invention has the advantages of good curative effect and high safety, so that the capsule is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a capsule for treating senile calcific heart valve disease and a preparation method thereof. Background technique [0002] Senile calcific valvular disease (SCHVD) mainly refers to the calcification of the connective tissue of the heart valve as the elderly grow older, resulting in abnormal valve or stent function. It is a common heart valve disease in the elderly and one of the important causes of heart failure and sudden death in the elderly. Cardiac echocardiography provides a reliable diagnostic basis for senile calcific valvular heart disease. With the prolongation of human lifespan, the incidence of senile calcific valvular heart disease is increasing year by year. The pathogenesis of the disease is unclear, but it is more common in patients with pre-existing atherosclerosis, most often on the ventricular surface of the posterior lobe. The evolution of the dis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/48A61P9/00A61K35/583
Inventor 陈风彩赵春丽孙阳姜传武徐茂航
Owner 烟台力量知识产权服务有限公司
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