Granules for treating alcoholic cardiomyopathy arrhythmia and preparation method thereof

Abstract

The invention discloses a method for preparing granules for treating alcoholic cardiomyopathy arrhythmia. The granules are applied to the therapy of alcoholic cardiomyopathy. The method is characterized by comprising the steps of (1) distilling Litchi chinensis Sonn., Stachys kouyangensis(Van.) Dunn and Aeschynomene indica L. by water vapor, so as to extract volatile oil for later use, and enabling dregs to be standby; (2) crushing Gekko gecko Linnaeus and Setaria italica (L.) Beauv. into fine powder for later use; (3) uniformly mixing Selaginella tamariscina (Beauv.) Spring, Begonia handelii Irmsch., Poncirus tuifoliata (L.) Raf., Polygonum aviculare L., Magnolia amoena Cheng, Dracocephalum moldavica L., Callicarpa nudiflora Hook. Et Arn. and the dregs obtained in the step (1), carrying out ethanol extraction twice, merging two alcohol extracts, filtrating, recovering ethanol, and carrying out depressurized concentration, so as to form an extract; (4) adding the fine powder obtained in the step (2) into the extract obtained in the step (3), uniformly mixing, drying at the temperature of 60 DEG C, crushing into fine powder, adding polysorbate-80, granulating, drying, finishing, spraying the volatile oil obtained in the step (1), uniformly mixing, and packaging granules, thereby obtaining the granules. Proved by clinical trials, the granules have the characteristics of good treatment effect and relatively high safety in the therapy of alcoholic cardiomyopathy, so that the granules are worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method of arrhythmia granules for treating alcoholic cardiomyopathy. Background technique [0002] Alcoholic cardiomyopathy (alcoholic cardiomyopathy.ACM) has an insidious onset and is more common in those who drink a lot of hard alcohol for more than 10 years. The general age of onset is over 40 years old, and there are more men than women. Symptoms vary among patients, mainly related to cardiac insufficiency and arrhythmia. Ethanol often causes diffuse myocardial damage, weakened myocardial beating, and reduced cardiac output. Alcohol damage to the myocardium may first manifest as arrhythmia, and if the heart disease is mild at this time, this arrhythmia is often considered non-pathological. Electrocardiographic examination often shows non-specific changes such as ST-T changes and left ventricular hypertrophy, accompanied by atrial and ventricular ar...

AI Technical Summary

Problems solved by technology

However, the current clinical treatment is mostly based on the treatment of deficiency syndromes, and t