Preparation method of Xingbei relieving cough and expectorant oral liquid

Abstract

The invention discloses a preparation method of a semen armeniacae amarae and thunberg fritillary bulb oral liquid for relieving cough and resolving phlegm. The preparation method is characterized by comprising the following steps of: jointly decocting sweet root bark of white mulberry, fried semen armeniacae amarae, thunberg fritillary bulb and liquorice to reserve an extracting liquid, obtaining clear paste through three-effect decompression concentration, sinking the clear paste by water and centrifugalizing and reserving a clear liquid; independently decocting sweet polygala tenuifolia, independently storing the extracting liquid, and combining the extracting liquid with the clear liquid; adjusting the pH twice when the volume is fixed and before filling; sterilizing for 40 minutes at 103 DEG C and filling. The preparation method disclosed by the invention has the beneficial effects that 1, the polygala tenuifolia is independently decocted to avoid the problem that the polygala tenuifolia is bubbled to lead to loss of effective components when the extracting liquid is concentrated; 2, three-effect decompression concentration is adopted, so that not only can the concentration temperature be low, the moisture is quick to evaporate, the concentration time is short and the energy consumption is reduced, but also the effective components of the product are effectively prevented from being damaged by high temperature foremost; 3, the pH value is adjusted twice to ensure the stability of product quality; 4, insulative overnight aging at 70-80 DEG C can be used for effectively preventing the liquid medicine from rancidity; 5, the oral liquid is sterilized for 40 minutes at 103 DEG C, and the temperature is moderate, so that the effective components of the liquid medicine are effectively protected.

Description

technical field [0001] The invention relates to a preparation method of an oral liquid, in particular to a preparation method of an apricot shell cough-relieving and expectorant oral liquid, which belongs to the technical field of medicine. Background technique [0002] In the official reply (98) Jingwei Yaozhi Shenzi No. 116, the prescription and preparation method of "Xingbei Oral Liquid for Cough and Phlegm Relief" is given: [0003] Prescription: mulberry bark 90g bitter almond 90g [0004] Fritillaria 120g Licorice 15g [0005] Polygala 45g [0006] Preparation method: decoct the above five flavors with water twice, 1.5 hours each time, combine the decoction, filter, concentrate the filtrate to a clear paste with a relative density of 1.20-1.25 (50°C), add 3 times the amount of water, and refrigerate for 12 hours, centrifuge, take the supernatant, add 125g of sucrose, and an appropriate amount of water, boil, filter, adjust the total amount of filtrate to...

AI Technical Summary

Problems solved by technology

[0008] 1. The extract is easy to foam during the process of concentrating to obtain clear ointment, and the active ingredients in the liquid medicine will evaporate with the water in the foam, so it is difficult to store the active ingredients in the liquid medicine;

[0009] 2. The temperature of the concentration process after the extraction of the clear ointment is high, high energy consumption and high heat source are not conducive to environmental protection, the comfort of personnel is not good, and the high temperature is concentrated for a long time, which will damage the active ingredients of the clear ointment and affect the curative effect;

[0010] 3. The pH value of the product is unstable and changes significantly with temperature;

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