Three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration

Abstract

The invention has the advantages that the signal to noise ration of the three dimensional magnetic resonance vascular wall imaging is improved effectively, and meanwhile, high isotropy resolution ratio is obtained. The invention provides a three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration as shown in figure 1. The three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration comprises a motion-sensitizing driven equilibrium prepulse part 1, a fat suppressed sequence part 2, a three dimensional rapid gradient echo sequence part 3 and a signal relaxation part 4. When the sequences are carried out, the four parts must be carried out in sequence. According to three dimensional vascular wall imaging sequence with rapid high isotropy resolution ration, when the three dimensional rapid gradient echo scanning is carried out, a sub-sampling method of compressed sensing is adopted to carry out sampling to the three dimensional K space, meanwhile, in order to effectively control a blood signal during the sampling, the sampling is carried out according to the pseudo intermediate sequence, after the sampling is accomplished, the data is recovered effectively by adopting nonlinear reconstruction method on the basis of sub-sampling data, so that the high quality three dimensional vascular wall image is obtained.

Description

technical field [0001] The invention is a radio frequency pulse sequence for magnetic resonance vessel wall and plaque imaging, which can provide fast and high isotropic resolution, can be used to diagnose carotid artery stenosis, detect intravascular plaque calcification, plaque Volume and plaque composition. Background technique [0002] Stroke due to atherosclerosis is a major cause of disability and death worldwide. According to literature, 4.4 million people will lose their lives every year, and 5,000 people per million will become disabled due to diseases. According to the notice given by the Ministry of Health on October 10, 2012, the population who died of cardiovascular and cerebrovascular diseases accounted for 41% of the total death rate in China. Although there are many causes of stroke, thrombus and embolism caused by the rupture of atherosclerotic plaque in the internal carotid artery are considered to be the main causes of stroke and transient ischemic attac...

AI Technical Summary

Problems solved by technology

However, the motion-sensitive driven balanced prepulse has the following disadvantages: (1) the inherent T2 attenuation effect will cause the signal-to-noise ratio (SNR) of the vessel wall image obtained by this technique to be about 20% lower than that of other sequences; (2) The amplitude of its motion-sensitive gradient is generally large, so it will cause eddy currents and affect the aggregation of static signals, thereby causing further loss of signals and affecting the diagnostic value of images; (3) Since there are two 180° hard pulses, it will make radio frequency (RF) power precipitation (specific absorption rate, SAR) increased, may cause discomfort to the patient

Because of the disadvantages (1) and (2), the layer thickness of 3D MERGE imaging cannot be too thin, so high isotropic resolution (such as 0.6 mm isotropic resolution) cannot be further obtained, so that a more accurate Vessel wall and plaque measurements

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