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Traditional Chinese medicinal composition for treating fever in children as well as preparation method and application thereof

A technology of children's fever and composition, which is applied in the direction of drug combination, antipyretics, and pharmaceutical formulas, can solve the problems of toxic side effects, cell damage, etc., and achieve the effect of rapid development, visceral qi clearing, and viscera tenderness

Inactive Publication Date: 2014-11-05
鞠建明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

High heat can cause dehydration, convulsions, and cell destruction. If chemical drugs are used, they will have relatively large toxic and side effects. At present, there is a lack of a safe and effective traditional Chinese medicine preparation for treating fever in children

Method used

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  • Traditional Chinese medicinal composition for treating fever in children as well as preparation method and application thereof
  • Traditional Chinese medicinal composition for treating fever in children as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Example 1: Take 6g of Scutellaria baicalensis, 8g of Viola chinensis, 6g of mallow seeds, 7g of gypsum, 6g of Schizonepetae, 12g of Guanzhong, 6g of forsythia, 12g of kudzu root, 6g of scutellaria baicalensis, 12g of scrophulariaceae, 6g of rehmannia, and 12g of windproof medicinal materials. , add water to decoct twice, add water for the first time to 10 times the weight of the medicinal material, decoct for 1.5h, add water for the second time to 8 times the weight of the medicinal material, decoct for 1.5h, combine the decoction, 0.07MPa, 60- Concentrate under reduced pressure at 70°C to extract with a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, let stand for 24 hours, filter, and filtrate Concentrate under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 at 65°C, and recover ethanol to obtain a concentrated solution, which is spray-dried (conditions are that the inlet air temperature is 1...

Embodiment 2

[0025] Example 2: Take 9g of Scutellaria baicalensis, 6g of Viola chinensis, 9g of mallow seed, 5g of gypsum, 9g of Schizonepetae, 9g of Guanzhong, 9g of forsythia, 9g of kudzu root, 9g of scutellaria baicalensis, 9g of scrophulariaceae, 9g of raw land, and 9g of Fangfeng. , add water to decoct twice, add water for the first time to 8 times the weight of the medicinal material, decoct for 1 hour, add water for the second time to 6 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, 0.07MPa, 60-70℃ Concentrate under reduced pressure to 65 ° C when the relative density is 1.20, add 95% (v / v) ethanol to make the alcohol content reach 80% (v / v), stir, let stand for 24 hours, filter, the filtrate is at 0.07MPa, 65 Concentrate under reduced pressure at ℃ to a relative density of 1.30 at 65℃, and recover ethanol to obtain a concentrated solution, filter, add water and sucrose to prepare an oral solution.

Embodiment 3

[0026] Example 3: Take 12g of Scutellaria chinensis, 4g of Viola chinensis, 12g of mallow seed, 3g of gypsum, 12g of Schizonepeta, 6g of Rhizoma chinensis, 12g of forsythia, 6g of kudzu root, 12g of scutellaria baicalensis, 6g of scrophulariaceae, 12g of rehmannia, and 6g of Fangfeng. , add water to decoct twice, add water for the first time to 12 times the weight of the medicinal material, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal material, decoct for 2 hours, combine the decoction, 0.07MPa, 60-70℃ Concentrate under reduced pressure to an extract with a relative density of 1.20 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, let stand for 24 hours, filter, and the filtrate is at 0.07 MPa, 65 DEG C reduced pressure concentration to 65 DEG C when the relative density is 1.30, and recovery of ethanol, concentrated solution, the concentrated solution is spray-dried (the condition is that the air inle...

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Abstract

The invention provides a traditional Chinese medicinal composition for treating fever in children. The composition is characterized by being prepared from the following raw materials in parts by weight: 6 to 12 parts of yam rhizome, 4 to 8 parts of Chinese violet, 6 to 12 parts of chingma abutilon seed, 3 to 7 parts of gyp, 6 to 12 parts of schizonepeta, 6 to 12 parts of cyrtomium rhizome, 6 to 12 parts of fructus forsythiae, 6 to 12 parts of kudzuvine root, 6 to 12 parts of baical skullcap root, 6 to 12 parts of radix scrophulariae, 6 to 12 parts of raw rehmannia root, and 6 to 12 parts of divaricate saposhnikovia root. By adopting a corresponding preparation method, oral solution, tablets, capsules or granules can be prepared. The traditional Chinese medicinal composition has the functions of dispelling wind and clearing heat, nourishing yin and removing toxicity, and can be used for treating fever in children.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating fever in children, a preparation method and application thereof. Background technique [0002] Children in the growth and development stage often have immature nervous systems and are easily disturbed by factors such as climate, environment, improper feeding, diseases, and drugs. This is the fundamental reason why children are prone to fever in summer. Fever, the first "protective wall" in the body Fever is a symptom and a normal immune response in the body, which can help kill bacteria and improve resistance. When fever occurs, various immune functions in the body are "activated", metabolism increases, antibody synthesis increases and phagocyte activity increases. High heat can cause dehydration, convulsions, and cell destruction. If chemical drugs are used, they will have relatively large toxic and s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P29/00A61K33/06
Inventor 鞠建明刘克冕
Owner 鞠建明
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