Refractive index solution standard substance and preparation method thereof

Abstract

The invention discloses a refractive index solution standard substance and a preparation method thereof. Various inorganic substances and organic substances, which meet purity requirements, are taken as raw materials; the coverage range of the refractive index is from 1.33 to 1.72; and the refractive index can be traced back to a refractive index meter with a maximum error ranging from -0.00002 to 0.00002, and also traced back to a refractive index standard block made of a glass material with an uncertain degree of 5*10-6. The preparation method comprises the steps that ethanol, cane sugar, sodium chloride, ethylene glycol, normal heptane, isooctane, cyclohexane, tetrachloroethylene, 1-iodonaphthalene, chloronaphthalene and diiodomethane with refractive indexes meeting the purity requirements are taken as raw materials; and each batch of raw materials are marked with batch numbers in detail, is mixed uniformly at random, then samples in one fifth quantity of the batch of the samples are extracted at random, and a value is defined by a high-accuracy refractive index meter with a measuring error of 2*10-5 at the temperature ranging from 19.8 DEG C to 20.2 DEG C. The refractive index solution standard substance can serve as a quality control product for daily testing in industries such as pharmaceuticals, essence and flavor, food additives and the like, so that high efficiency, reliability and stability of a production process can be guaranteed. The substance can further serve as a standard reference material for testing mechanisms of food, drug, essence and flavor products, and provides an assurance for the quality supervision and inspection of the types of the products.

Description

technical field [0001] The invention relates to a medicine, flavor and fragrance and food additive solution standard substance and a preparation method thereof, in particular to a refractive index solution standard substance and a preparation method thereof. Background technique [0002] In the detection of medicine, flavors and fragrances and food additives, the refractive index of the solution is an important means to identify and quantify soluble solids, and is an important indicator related to food quality and food safety. At present, there are many methods for detecting the refractive index of solutions, and the most commonly used ones are Abbe refractometers, hand-held refractometers and bench-top refractometers based on the principle of total reflection angle or minimum deflection angle. These instruments have a nominal refractive index measurement accuracy of 10 -5 order of magnitude. However, for a long time, the standard material with the highest accuracy in ...

AI Technical Summary

Problems solved by technology

However, for a long time, the standard material with the highest accuracy in my country can only reach the order of 10-4, which cannot guarantee the accuracy and reliability of the measurement results of high-precision instruments