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Heart-care medicine composition as well as preparation method and application thereof

A technology of composition and medicine, which is applied in the field of Lixin pharmaceutical composition and its preparation, can solve problems such as large side effects, achieve the effects of reducing impurities, improving animal hypoxia tolerance, and taking a small dose of medicine

Inactive Publication Date: 2013-03-13
吉林国药制药有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing drugs for treating heart disease mostly use western medicine ingredients, which have severe side effects. Therefore, research on pharmaceutical compositions using traditional Chinese medicine ingredients has become an important topic for current researchers

Method used

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  • Heart-care medicine composition as well as preparation method and application thereof
  • Heart-care medicine composition as well as preparation method and application thereof
  • Heart-care medicine composition as well as preparation method and application thereof

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Embodiment Construction

[0015] A medicinal composition for benefiting heart, comprising the following ingredients: mink heart 255g, poria cocos 1450g, rehmannia glutinosa 1160g, asparagus 406g, moutan cortex 290g, amber 87g, cinnabar 58g, and fangji 290g.

[0016] According to the preparation method of a Lixin pharmaceutical composition according to the present invention: cinnabar is water-flyed or crushed into fine powder I; amber is crushed into fine powder II; mink heart is decocted twice, the first time is 3 hours, the second time After 2 hours, combine the decoctions, filter, add 5% beeswax, mix, stand still, remove the beeswax, and concentrate the filtrate into extract I with a relative density of 1.20 (60°C); steam distill the Moutan cortex for 2 hours, and collect the effluent , placed at 10°C for 4 hours, collected the precipitated crystals, and crushed into fine powder III; Moutan cortex dregs were combined with Poria cocos, Rehmannia glutinosa, Asparagus, and Fangji, and extracted with wat...

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Abstract

The invention discloses a heart-care medicine composition as well as a preparation method and an application thereof. The heart-care medicine composition comprises the following components: 225 g of mink heart, 1450 g of poria cocos, 1160 g of radix rehmanniae, 406 g of asparagus cochinchinensis, 290 g of cortex moutan, 87 g of amber, 58 g of cinnabar and 290 g of radix stephaniae tetrandrae. The medicine composition provided by the invention has the efficacy of treating the rheumatic heart disease, arrhythmia, heart failure and the like; pharmacodynamic data show that animal hypoxia tolerance is improved, the model animal heart rate and T wave changes of experimental acute myocardial ischemia model rats caused by pituitrin (Pit) can be remarkably improved, the rise of the blood serum CK (Creatinekinase), LDH (Lactic dehydrogenase) and AST (Aspartate aminotransferase) values of a model animal can be obviously improved; and meanwhile, based on the preparation method provided by the invention, the extraction rate of the effective components is higher, and impurities are reduced, so that the dosage for a patient is smaller, and conditions for developing other preparations based on the medicine composition are created.

Description

[0001] technical field [0002] The present invention relates to the field of medicines, more specifically, to a Lixin pharmaceutical composition and its preparation method and application. [0003] Background technique [0004] Most of the existing drugs for treating heart disease use western medicine ingredients, which have great side effects. Therefore, the study of pharmaceutical compositions using traditional Chinese medicine ingredients has become an important topic for current researchers. [0005] Contents of the invention [0006] The technical problem to be solved by the present invention is to provide a heart-reinforcing pharmaceutical composition for treating heart diseases, its preparation method and application. [0007] The purpose of the present invention is achieved through the following technical solutions: [0008] A medicinal composition for benefiting heart, comprising the following ingredients: mink heart 255g, poria cocos 1450g, rehmannia glutino...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8965A61P9/00A61P29/00A61P9/06A61P9/04A61P9/10
Inventor 陈用芳秦剑
Owner 吉林国药制药有限责任公司
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