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High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning

A biosafety and detection instrument technology, applied in the direction of instruments, scientific instruments, measuring devices, etc., can solve the problems of biological sample contamination operation platform, increase the risk of biological contamination, and biological sample dripping, so as to increase the advantages of high throughput, Enhanced biosecurity protection, exposure avoidance effects

Inactive Publication Date: 2013-02-27
WUHAN EASYDIAGNOSIS BIOMEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there is a mode of using a scanner to collect images for detection in foreign countries, the scanning surface is upward, so when used for reagent detection, the reagents that have been added to the instrument must be reacted outside the instrument before they can be tested on the machine, otherwise the reagents that have just been added to the sample will be detected. When placed upside down, the biological sample that has not been fully absorbed in the sample injection hole will drop onto the scanning interface, causing biological sample contamination
Therefore, the biggest disadvantages of the detection mode with the conventional scanning interface facing upwards are: 1) One-step detection cannot be performed, and detection on the machine needs to be completed after the off-machine reaction is completed; 2) Even if the off-machine reaction is completed, the detection reagent needs to face down However, there is still a risk of biological samples contaminating the operating platform; 3) Because the reagents need to be turned upside down, the operator must come into contact with the reagents that already contain biological samples, which increases the risk of biological contamination

Method used

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  • High-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1: Quantitative detection of D-dimer in human whole blood (or serum / plasma) (colloidal gold method)

[0032] 1) Start the instrument and run to the operation interface;

[0033] 2) Adding samples for detection: tear open the package of 5 D-dimer quantitative detection kits (colloidal gold method) and place them in the removable tray 4 of the instrument, corresponding to 5 whole blood D-dimer samples to be tested , take 80 μl of whole blood for each part and add it to the cartridge position 5 (sample hole) of the corresponding kit, push the tray into the reaction tank of the reagent placement platform 2, and click the detection button on the operation interface.

[0034] 3) Result output: The instrument automatically completes the test in 15 minutes, and the quantitative test results of 5 samples appear on the instrument interface. After entering the information of the tested person, save the result, and click the print button to print the test result.

[0035] ...

Embodiment 2

[0036] Example 2: Qualitative detection of D-dimer in human whole blood (or serum / plasma) (colloidal gold method)

[0037] 1) Start the instrument and run to the operation interface;

[0038] 2) Adding samples for detection: tear off the package of 3 D-dimer qualitative detection kits (colloidal gold method) and place them in the removable tray 4 of the instrument, corresponding to 3 samples of plasma D-dimer to be tested, Take 50 μl of plasma sample for each sample and add it to the cartridge position 5 (sample hole) of the corresponding kit, push the tray into the reaction tank of the reagent placement platform 2, and click the detection button on the operation interface.

[0039] 3) Result output: The instrument automatically completes the test in 15 minutes, and the test results of 5 samples (negative or positive) appear on the instrument interface. After entering the information of the tested person, save the result, and click the print button to print the test result.

...

Embodiment 3

[0041] Example 3: Quantitative detection of N-terminal BNP precursor in human whole blood (or serum / plasma) (immunofluorescence method)

[0042] 1) Start the instrument and run to the operation interface;

[0043] 2) Adding samples for detection: Tear open the package of 1 N-terminal pro-BNP detection kit (immunofluorescence method) and place it in the removable tray 4 of the instrument, take 80 μl whole blood sample and add it to the cartridge of the kit After position 5 (sample hole), push the tray into the reaction tank of reagent placement platform 2, and click the detection button on the operation interface.

[0044] 3) Result output: The instrument will automatically complete the test in 15 minutes, and the quantitative test result will appear on the instrument interface. After inputting the information of the tested person, save the result, and click the print button to print the test result.

[0045] 4) Disposal of waste: The operator takes out the tray and directly pou...

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Abstract

The invention relates to a high-biosecurity POCT (Point of Care Testing) instrument based on image or sensitizing scanning, belonging to the field of reagent testing. The instrument comprises an image or sensitizing scanning device, a reagent holding platform and a data processing device. The image scanning area of the image or sensitizing scanning device faces downward, and the reagent holding platform is put above the image scanning area of the image or sensitizing scanning device. The reagent holding platform is movable and an operator does not need to touch the testing reagent added into a biological sample, so the biosecurity is improved. According to the invention, the scanning side of the image or sensitizing scanning device faces downward to read the information of the testing reagent, and the testing reagent faces up, so the biological sample can not outflow; and the reagent holding platform is movable and the operator does not need to touch the testing reagent which contains the biological sample, so the biosecurity protection in the working process is improved.

Description

technical field [0001] The invention relates to a high biosafety point-of-care detection (POCT) instrument based on image or photosensitive scanning, which belongs to the technical field of reagent detection. Background technique [0002] Point-of-care detection (POCT) has been widely used in the field of reagent detection technology at home and abroad because of its simplicity and rapidity. The current real-time detection instruments mostly use a camera or a single photosensitive element to collect the information of the detection reagent, the collection area is small, and most of them can only perform single reagent detection. Although there is a mode of using a scanner to collect images for detection in foreign countries, the scanning surface is upward, so when used for reagent detection, the reagents that have been added to the instrument must be reacted outside the instrument before they can be tested on the machine, otherwise the reagents that have just been added to t...

Claims

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Application Information

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IPC IPC(8): G01N21/84G01N21/01
Inventor 陈莉莉王颖
Owner WUHAN EASYDIAGNOSIS BIOMEDICINE
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