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Oyster lipid-lowering capsule and preparation method

A technology of capsules and oysters, which is applied in the field of drug preparation and can solve problems such as adverse reactions

Inactive Publication Date: 2013-01-09
北海蓝海洋生物药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Overcome the shortcomings of existing lipid-lowering drugs that produce adverse reactions while lowering lipids

Method used

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  • Oyster lipid-lowering capsule and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Recipe: 80kg oyster meat, 45kg rhubarb, 8kg American ginseng

[0058] Ophiopogon japonicus 30 kg;

[0059] Preparation:

[0060] (1) Extraction of oyster polysaccharides: take oyster meat, wash it, stir the slurry evenly, add hydrochloric acid to adjust the pH value to 6.0, heat it in a water bath to 75-80°C for 5 hours, filter, repeat 3 times, combine the filtrate, centrifuge, take the centrifuge When the solution is concentrated at 100°C to 60°C, the thermal relative density is 1.15 to obtain a concentrated solution, 96 kg of 90% ethanol is added to the concentrated solution for alcohol precipitation, and the precipitated crude polysaccharide is obtained after filtration for subsequent use;

[0061] (2) Extraction of American ginseng, rhubarb and Ophiopogon japonicus: get American ginseng and pulverize into 24 mesh fine powder, rhubarb and Ophiopogon japonicus are pulverized into coarse powder with a particle diameter of 0.1-0.5 cm, combine the above-mentioned medici...

Embodiment 2

[0064] Recipe: 120kg oyster meat, 60kg rhubarb, 12kg American ginseng

[0065] Ophiopogon japonicus 40 kg;

[0066] Preparation:

[0067] (1) Extraction of oyster polysaccharides: take oyster meat, wash it, stir the slurry evenly, add hydrochloric acid to adjust the pH value to 6.0, heat it in a water bath to 75-80°C for 5 hours, filter, repeat 3 times, combine the filtrate, centrifuge, take the centrifuge When the solution is concentrated at 100°C to 60°C, the thermal relative density is 1.15, and the concentrated solution is obtained. 144 kg of 90% ethanol is added to the concentrated solution for alcohol precipitation, and the precipitated crude polysaccharide is obtained after filtration for subsequent use;

[0068] (2) Extraction of American ginseng, rhubarb and Ophiopogon japonicus: get American ginseng and pulverize into 24 mesh fine powder, rhubarb and Ophiopogon japonicus are pulverized into coarse powder with a particle diameter of 0.1-0.5 cm, combine the above-ment...

Embodiment 3

[0071] Recipe: 100kg oyster meat, 48kg rhubarb, 10kg American ginseng

[0072] Ophiopogon japonicus 32 kg;

[0073] Preparation:

[0074] (1) Extraction of oyster polysaccharides: take oyster meat, wash it, stir the slurry evenly, add hydrochloric acid to adjust the pH value to 6.0, heat it in a water bath to 75-80°C for 5 hours, filter, repeat 3 times, combine the filtrate, centrifuge, take the centrifuge When the solution is concentrated at 100°C to 60°C, the thermal relative density is 1.15 to obtain a concentrated solution, 120 kg of 90% ethanol is added to the concentrated solution for alcohol precipitation, and the precipitated crude polysaccharide is obtained after filtration for subsequent use;

[0075] (2) Extraction of American ginseng, rhubarb and Ophiopogon japonicus: get American ginseng and pulverize into 24 mesh fine powder, rhubarb and Ophiopogon japonicus are pulverized into coarse powder with a particle diameter of 0.1-0.5 cm, combine the above-mentioned med...

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Abstract

The invention discloses an oyster lipid-lowering capsule and a preparation method. In known technologies, many drugs can achieve purposes of reducing total cholesterol, triglyceride and low density lipoprotein cholesterol, but any drug has adverse reactions. According to the oyster lipid-lowering capsule and the preparation method, marine organism oyster meat, rhubarb root and rhizome, American ginseng and dwarf lilyturf tuber are reasonably matched to prepare a drug which is capable of reducing blood index levels of total cholesterol, triglyceride and low density lipoprotein cholesterol in human blood and simultaneously can not produce adverse reactions which are not beneficial to human bodies. The result of a pharmacodynamics test shows that the oyster lipid-lowering capsule is capable of inhibiting rising of total cholesterol, triglyceride and low density lipoprotein cholesterol of quail and has similar functions of reducing blood lipid as evening primrose oil, but the oyster lipid-lowering capsule has obvious advantages in reducing triglyceride so that the oyster lipid-lowering capsule has good functions of adjusting blood lipid.

Description

technical field [0001] The invention relates to an oyster Jiangzhi capsule, which is used for reducing the blood lipid level of a human body. The invention also relates to a preparation method of the oyster Jiangzhi capsule, which belongs to the technical field of medicine preparation. Background technique [0002] Elevated levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) in human blood have a great relationship with the normal flow of human blood. When they exceed a certain level , it will block the normal flow of cold blood and cause infarction, so it is very meaningful to keep the blood indicators normal. However, people's bad eating habits in real life often increase the level of indicators in the blood and form thrombus, thus endangering people's health. Therefore, reducing the levels of total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) in human blood has become a goal pursued...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P3/06A61K35/56A61K35/618
Inventor 邹贤刚梁祖珍
Owner 北海蓝海洋生物药业有限责任公司
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