Medical plastic bone cement

A bone powder and bone defect technology, applied in the field of medical biomaterials, can solve the problems of high sales price and difficult shaping

Inactive Publication Date: 2012-10-31
TIANJIN SANNIE BIOENG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] More importantly, the current domestic and foreign artificial bone and bone joint material specifications also widely use non-shape or hard-to-shape products, and the sales price is very expensive.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Take 1.5 g of commercially available chitosan hydrochloride, add it into 10 ml of deionized water, and stir evenly to make a polysaccharide glue with a concentration of 25%. Take 2.5 g of 60-mesh bone meal made by crushing commercially available heterogeneous bone, add it to the above-mentioned polysaccharide glue, and stir it into a puree to obtain a bone paste. The weight ratio of bone powder to polysaccharide is 5:3.

Embodiment 2

[0014] Take 4.5 g of commercially available carboxylated chitosan, add 10 ml of deionized water, stir evenly to make a polysaccharide glue with a concentration of 45%. Take 13.5 g of 180-mesh bone powder made from commercially available bone of the same kind and mash it, add it to the above-mentioned polysaccharide glue, and stir it into a puree to obtain a bone paste. The weight ratio of bone powder to polysaccharide is 3:1.

Embodiment 3

[0016] Take 5 g of commercially available chitosan lactate, add 100 ml of deionized water, stir evenly to make a polysaccharide glue with a concentration of 5%. Take 40 g of 30-mesh bone powder made by mashing commercially available collagen-based bone repair materials, add it to the above-mentioned polysaccharide glue, and stir it into a slurry to obtain a bone slurry. The weight ratio of bone powder to polysaccharide is 8:1.

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PUM

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Abstract

The invention discloses a plastic material capable of being used for clinical bone stuffing and repair, belongs to the field of medical biomaterial, and aims to solve the problem that at present, bone repair material used clinically has a fixed and regular shape and can not be shaped at will. The material provided by the invention is prepared by combining gummosity of polyose, protein and organic colloidal solution with the repair function of bone meal. The prepared material is stable, plastic and gummous bone cement stuffing, helps complete stuffing of detect parts in the orthopedics department, and reinforces the bone formation effect.

Description

technical field [0001] The invention relates to a composite material of bone powder and polysaccharide or protein glue or organic binder. For bone filling and repair. The invention belongs to the technical field of medical biomaterials. Background technique [0002] Human bone repair technology has gone through a long period of development, mainly in the biocompatibility of materials has made great improvements, from the original wicker to metal, and then to medical polymers, now bone repair materials have entered the bionic material stage. However, no matter what kind of material it is, there has not been much improvement in the means of clinical use. Basically, materials that are not easy to shape, such as granules or strips, are still used. It is very inconvenient to operate for fractured or non-union bone sutures. Due to trauma, tumor, pathological disease or other forms of bone trauma and bone implantation in the Department of Stomatology, the shape of the bone defe...

Claims

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Application Information

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IPC IPC(8): A61L27/44A61L27/36A61L27/24A61L27/22A61L27/20A61L27/16
Inventor 毕宏伟谢磊
Owner TIANJIN SANNIE BIOENG TECH
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