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Medicine composition for curing myelofibrosis and hepatofibrosis and preparation method of medicine composition

A technology for bone marrow fibrosis and liver fibrosis, applied in the field of medicine, to achieve the effects of low toxicity, reduction of liver fibrous tissue, and improvement of liver function

Active Publication Date: 2012-09-19
石家庄平安医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific drug treatment for this disease, and comprehensive treatments such as antiviral, immune regulation, liver function recovery and anti-fibrosis are mostly used.

Method used

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  • Medicine composition for curing myelofibrosis and hepatofibrosis and preparation method of medicine composition

Examples

Experimental program
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Effect test

Embodiment 1

[0043] A pharmaceutical composition for treating bone marrow fibrosis and liver fibrosis. The main medicinal raw materials of the pharmaceutical composition are: 240 vinegar turtle shells; 320 fried peach kernels; 80 cooked rhubarb; 120 trigonum; Leech 320; Dihuang 120; Ziheche 40; Sanqi 24; Licorice 80. Its preparation steps include:

[0044] A, take by weighing each effective raw material according to above-mentioned formula, wherein vinegar turtle shell, cooked rhubarb, leech, Ziheche, Panax notoginseng are pulverized into fine powder;

[0045] B. Stir-fried peach kernels, sanleng, rehmannia glutinosa, and licorice, add water and decoct 3 times, 1 hour each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.15g / ml~1.25g / ml (50℃~ 60℃) clear paste;

[0046] C. Add the fine powder obtained in step A to the clear paste of step B, mix well, dry, pulverize into fine powder, and sieve;

[0047] D, every 100g of the powder obtained in st...

Embodiment 2

[0049] A pharmaceutical composition for treating bone marrow fibrosis and liver fibrosis. The main medicinal raw materials of the pharmaceutical composition are: vinegar turtle shell 230; fried peach kernel 340; cooked rhubarb 80; sanleng 130; Leech 340; Dihuang 110; Ziheche 45; Panax notoginseng 25; Licorice 75. Its preparation steps include:

[0050] A, take by weighing each effective raw material according to above-mentioned formula, pulverize into fine powder, sieve;

[0051] B. For every 100g of the obtained powder, add 27g to 33g of refined honey and add water to make 1000g of honeyed pills, and dry to obtain the finished product.

[0052] In addition, honey or other pharmaceutically acceptable excipients can be added to the dry paste, thick paste or powder mixture prepared in the above embodiments of the present invention to make pills or other clinically acceptable granules, dropping pills, tablets, Capsules, suspensions, oral liquid preparations, etc.

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Abstract

The invention discloses a medicine composition for curing myelofibrosis and hepatofibrosis and a preparation method of the medicine composition. The main raw materials of the medicine composition include, by weight, 200-300 of vinegar turtles, 300-400 of fried peach seeds, 50-150 of cooked rhubarb, 100-200 of common burreed rhizome, 300-400 of leeches, 100-200 of rehmannia roots, 10-110 of human placenta, 10-110 of panax notoginseng and 50-150 of liquorice. The preparation method comprises steps of weighing the raw materials in accordance with the above prescription, uniformly mixing the raw materials through smashing and water-extraction concentration or a combination method of the smashing and the water-extraction concentration and obtaining the medicine composition. The medicine composition can soften hard lumps and dispel nodes, removes blood stasis for promoting tissue regeneration and nourishes blood and can be used for curing syndromes such as accumulation lumps under the rib side, sallowness, weakness, palpitation, shortness of breath, primary myelofibrosis, liver cirrhosis, hepatosplenomegaly and anemia which are caused by blood stasis and non-generation of new blood.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a pharmaceutical preparation made from plant Chinese herbal medicines and used for softening and resolving hard masses, removing blood stasis and promoting regeneration, nourishing blood and promoting blood production, and a preparation method thereof. Background technique [0002] Myelofibrosis, also known as bone marrow sclerosis, manifests as hepatosplenomegaly and anemia. It belongs to the category of "'disease accumulation'" in traditional Chinese medicine. Liver meridian, the liver stores blood, heat and toxins are combined with blood, accumulates and forms and sees accumulation under the side (hepatosplenomegaly), blood stasis does not dispel, new blood does not produce, and deficiency symptoms such as jaundice and fatigue appear. Liver fibrosis is an important pathological feature of chronic liver disease, and it is also an inevitable stage of liver cirrhosis. This dis...

Claims

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Application Information

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IPC IPC(8): A61K36/902A61P19/08A61P1/16A61P7/06
Inventor 黄怀鹏刘清池李建英陶君李静涵
Owner 石家庄平安医院有限公司
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