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Medicine composition for treating gout, as well as preparation method and application of medicine composition

A composition and drug technology, applied in the field of pharmaceutical composition for treating gout and its preparation and use, to achieve good anti-inflammatory effect, good therapeutic effect, and effect of reducing blood uric acid

Inactive Publication Date: 2012-08-15
CHONGQING ACAD OF CHINESE MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no study on the treatment of gout after the compatibility of traditional Chinese medicine 菥蓂 and Qinpi

Method used

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  • Medicine composition for treating gout, as well as preparation method and application of medicine composition
  • Medicine composition for treating gout, as well as preparation method and application of medicine composition
  • Medicine composition for treating gout, as well as preparation method and application of medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0028] Prescription proportioning: 100g of 菥蓂, 100g of Qinpi;

[0029] According to the above ratio, take the scorpion, add 15 times the amount of water to extract 3 times, each time for 1 hour, and concentrate; then take Qinpi and add 60% V / V ethanol to reflux extract 3 times, each time for 1 hour, and concentrate. Combining the extracts of the sageria and bark, adding an appropriate amount of starch and dextrin, and granulating to obtain the pharmaceutical composition granules of the present invention.

Embodiment 2

[0030] The preparation of embodiment 2 pharmaceutical compositions of the present invention

[0031] Prescription proportioning: 500g of 菥蓂, 100g of Qinpi;

[0032] According to the above proportions, take the scorpion, add 10 times the amount of water to extract 3 times, each time for 0.5 hours, and concentrate; then take Qinpi and add water to extract 3 times, each time for 0.5 hours, and concentrate. Combining the extracts of the sageriae and bark bark, concentrating and drying, adding an appropriate amount of soluble starch and dextrin, granulating, and compressing into tablets to obtain the pharmaceutical composition tablet of the present invention.

Embodiment 3

[0033] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0034] Prescription proportioning: 1000g of 菥蓂, 100g of Qinpi;

[0035] According to the above proportions, take the scorpion and chinensis, first add 12 times the amount of water to extract 3 times, each time for 0.5 hours, combine the water extracts, after concentration and drying, add an appropriate amount of microcrystalline cellulose, and pack them into capsules to obtain the pharmaceutical combination of the present invention. capsules.

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PUM

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Abstract

The invention discloses a medicine composition for treating gout, which is a preparation prepared from bulk pharmaceutical medicines in weight proportion: 1-10 parts of thlaspi arvense and 1-10 parts of ash bark. The invention also provides a preparation method and application of the medicine composition. According to the invention, the thlaspi arvense and the ash bark are compounded by adopting a specific proportion, thus a cooperative synergistic effect is developed, and the medicine effect of a mixture of the thlaspi arvense and the ash bark is remarkably superior to that of the thlaspi arvense or ash bark under the same dosage. The medicine composition can remarkably reduce blood uric acid, is better in anti-inflammatory effect, has better treatment functions for gout and acute gouty arthritis, and provides a new selection for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating gout, a preparation method and application thereof. Background technique [0002] Gout is a kind of crystalline arthritis caused by purine metabolism disorder and / or decreased uric acid excretion. The clinical manifestations are characteristic acute arthritis caused by hyperuricemia and urate crystal deposition, tophi formation, tophi Chronic arthritis, urate nephropathy, uric acid urolithiasis, etc. may occur. In severe cases, joint disability and renal insufficiency may occur. The prerequisite for the onset of gout is hyperuricemia. Therefore, hyperuricemia is the most important biochemical basis of gout, followed by inflammatory reactions caused by urate deposition. In the past 20 years, with the changes in dietary structure (such as increased calorie intake and high-purine foods), increased intake of alcohol, especially beer drinks, and decreased physical activity, hyperuricemia an...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61P19/06A61P19/02A61P29/00
Inventor 杨荣平钟国跃罗先钦张小梅张丽张毅杨雪胡荣兰波杜洪飞王云红
Owner CHONGQING ACAD OF CHINESE MATERIA MEDICA
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