New application of arginine

Abstract

The invention discloses new application of arginine, which is the application of arginine or a pharmaceutically acceptable salt, an ester or a mixture of the salt and the ester in preparing topical pharmaceutic preparations with at least one of the following effects: (1) treating and / or facilitating wound healing, and (2) reducing scar formation. Results in pharmacodynamics experiments show that the external use of L-arginine can remarkably facilitate trauma healing of rat skin as well as reduce the area of a wound scar. Arginine not only can be used for treatment and healing of traumas but also can be used for other skin diseases, including a pressure ulcer (bedsore), skin injuries caused by dermatitis, scald, burn and the like.

Description

technical field [0001] The invention relates to a new application of arginine. Background technique [0002] 1. L-arginine background [0003] L-arginine [L-Arginine; abbreviation L-Arg; symbol R, scientific name: 2-amino-5-guanidino-pentanoic acid (S)-2-Amino-5-guanidinopentanoic acid] is a guanidino-containing The aliphatic basic amino acids are positively charged and alpha polar. L-arginine is involved in protein synthesis, and the codons in messenger ribonucleic acid (mRNA) are CGU, CGC, CGA, CGG, AGA, and AGG. In animals, arginine is a semi-essential or conditionally essential amino acid according to the developmental stage and individual physical conditions (for example, the human body cannot synthesize arginine in infants and young children; increased arginine requirements). Arginine was first isolated in 1886 from a lupine seed extract by Swiss chemist Ernst Schultze. D-Arginine has not been found in nature. L-arginine is widely found in animal and plant foods....

AI Technical Summary

Problems solved by technology

Although both iNOS and cNOS can participate in various inflammatory responses, iNOS can exacerbate the damage of body tissues in many disease conditions

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