Ardisia crenata sims extract and medicinal application thereof

A technology of extract and use, which is applied in the field of medical use of Octopus octopus extract, and can solve the problems such as the expression activity of TNFα that has not yet been seen

Inactive Publication Date: 2012-07-11
HUZHOU R & D CENT FOR NUTRITION & HEALTH SHANGHAI INST FOR BIOLOGICAL SCI CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no report about the inhibition of TNFα expression by Octopus and its extracts

Method used

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  • Ardisia crenata sims extract and medicinal application thereof
  • Ardisia crenata sims extract and medicinal application thereof
  • Ardisia crenata sims extract and medicinal application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1 Preparation of Octopus octopus extract

[0039] Take 100 g of Octopus octopus coarse powder, extract twice with 90% ethanol under reflux, each time for 1.5 hours, filter, combine the filtrates, concentrate the liquid extract under reduced pressure, freeze-dry to dryness. Obtain 13.18g of Octopus octopus extract.

Embodiment 2

[0041] Take 100 g of Octopus octopus powder, reflux extract with 30% ethanol three times, each time for 1 hour, filter, combine the filtrates, concentrate the liquid extract under reduced pressure, freeze-dry to dryness. Obtain 16.21g of Octopus octopus extract.

Embodiment 3

[0043] Get 100g of Octopus octopus powder, extract once with 95% ethanol under reflux for 3 hours, filter, combine the filtrates, concentrate the liquid extract under reduced pressure, freeze-dry to dryness. Obtain 12.03g of Octopus octopus extract.

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PUM

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Abstract

The invention relates to the field of pharmacological science, in particular to an ardisia crenata sims extract and a medicinal application thereof. The ardisia crenata sims extract can be applied to treatment of inflammatory diseases such as gouty arthritis and the like.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the medical application of a octopus extract. Background technique [0002] Eight-clawed Golden Dragon is the dry root and rhizome of Ardisia crispa (Thunb.) A.DC. It is flat in nature and bitter in taste, and has the effects of clearing heat and detoxifying, dissipating blood stasis and relieving pain, and expelling wind and dampness. It is mainly produced in Guizhou Province and has a large reserve. It is a traditional Chinese medicine in Guizhou. It is commonly used in the treatment of sore throat, tonsillitis, pain in the heart and stomach, hematemesis due to fatigue, bruises and rheumatic bone pain, etc. 411). [0003] Inflammation is the defense response of living tissue with vascular system to damage factors, manifested as redness, swelling, heat, pain and dysfunction. "Inflammatory disorder" refers to a group of disorders in which there is a pathological change of an inflammat...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P1/02A61P1/04A61P11/06A61P17/06A61P19/02A61P19/08A61P25/08A61P29/00A61P35/00A61P37/02A61P37/06
Inventor 王滔魏晨宗伟英肖功胜苏凡
Owner HUZHOU R & D CENT FOR NUTRITION & HEALTH SHANGHAI INST FOR BIOLOGICAL SCI CHINESE ACADEMY OF SCI
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