Device suitable for minim liquid mixed chemiluminescence reaction

Abstract

The invention relates to a device suitable for the minim liquid mixed chemiluminescence reaction. The device provided by the invention contains an upper cover plate and a lower plate which cooperate with each other. Two ends of the outer side of the upper cover plate are provided with alcoves. The central section of the inner side of the upper cover plate is provided with a micro-channel structure for flowing of the minim liquid. The micro-channel structure is divided into sample introduction, mixing and waste liquid outflow sections. An aperture is disposed over the mixing section of the micro-channel structure. An introduction port is disposed over the sample introduction section. A waste liquid outlet is disposed over the waste liquid outflow section. Two surface acoustic wave generation structures and a micro-heating and temperature control structure are positioned at the inner side of the lower plate. Each surface acoustic wave generation structure contains an interdigital electrode section and a Bragg reflection strip section. The micro-heating and temperature control structure contains a heating film resistor section and a temperature-measurement film resistor section. The reaction device provided by the invention can be used to fully mix two minim liquids, accurately control the temperature of the chemical reaction, and greatly enhance the efficiency of the chemiluminescence reaction.

Description

technical field [0001] The invention belongs to the technical field of applied micro-nano manufacturing, and relates to a detection device for chemical samples, in particular to a device suitable for micro-liquid mixed chemiluminescence reaction. Background technique [0002] The application of micro-nano manufacturing technology to integrate the functions of mixing, reaction and detection of chemical samples in a small volume can realize the miniaturization and cost reduction of the biochemical detection system. The microfluidic system formed by micro-nano manufacturing technology is easy to be integrated with the detection circuit to realize the automation and miniaturization of analytical instruments. [0003] Chemiluminescence is the reaction of two chemical samples mixed, accompanied by the light emission phenomenon produced by the chemical reaction process, the chemical sample components participating in the reaction can be determined by measuring the luminous intensit...

AI Technical Summary

Problems solved by technology

Currently widely used chemiluminescence instruments mostly use external mechanical oscillation to try to improve the mixing degree of trace liquids, but the effect is not obvious due to the small sample volume

In addition, these luminometers do not have the function of precise temperature control of the local microenvironment, and cannot fulfill the requirements of trace and high-efficiency chemiluminescent reactions.

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