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Nano-grade gynaecological lotion and preparation method thereof

A gynecological lotion, nano-level technology, applied in the field of medicine, can solve the problems of increasing the incidence of endometrial cancer, increasing the economic burden of patients, and producing drug resistance, so as to improve the bioavailability efficiency, reduce the dosage of drugs, reduce the Check the effect of fees

Inactive Publication Date: 2012-04-04
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicine has two main shortcomings in the treatment of vaginitis: (1) The antibacterial and anti-inflammatory drugs used in gynecology often stop at inhibiting one or a type of bacteria. A series of analysis checks to determine the type of infection before medication
Undoubtedly, it greatly increases the economic burden of patients
(2) Western medicines have large side effects, cannot be used for a long time, and will develop drug resistance
The commonly used drug metronidazole has teratogenic effects on the fetus, miconazole, etc. have certain damage to liver function, and hormone replacement method will increase the incidence of endometrial cancer and other diseases in patients

Method used

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  • Nano-grade gynaecological lotion and preparation method thereof
  • Nano-grade gynaecological lotion and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] 1) Weigh EL-4024 g, PEG-6002 g, almond oil 0.3 g, olive oil 1.7 g, myrrh oil 16 g, nano silver sol 4 g, aloe extract 2 g, glacial acetic acid 0.1 g, deionized water 49.9 g spare;

[0056] 2) Mix EL-40 and PEG-600 thoroughly;

[0057] 3) Add almond oil, olive oil, myrrh oil and nano-silver sol, and stir well;

[0058] 4) Slowly add deionized water at 20°C and stir thoroughly, and add aloe vera extract until a clear, transparent, yellow or colorless O / W nanoemulsion with low viscosity and fluidity is formed;

[0059] 5) Adjust the pH with glacial acetic acid.

Embodiment 2

[0061] Composed of RH-4020 g, 1,2-propanediol 8.3 g, glycerin 1.7 g, vitamin E oil 0.1 g, isopropyl myristate 0.1 g, myrrh oil 1 g, nano silver sol 3.8 g, aloe extract 5 g , 0.1 g of glacial acetic acid, and 59.9 g of deionized water.

Embodiment 3

[0063] Tween-80 36 g, Span-854 g, 1,2-propanediol 3 g, jojoba oil 5 g, myrrh oil 10 g, nano-silver sol 0.02 g, aloe extract 1.98 g, glacial acetic acid 0.1 g , 39.9 g of deionized water.

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Abstract

The invention discloses a nano-grade gynaecologic lotion, which is characterized in that: the granularity of the lotion is 1 to 100nm, the lotion is made of the following raw materials in percentage by weight: 20 to 40 percent of surface active agent, 1 to 10 percent of cosurfactant, 0.2 to 5 percent of oil phase, 1 to 20 percent of myrrh oil, 0.02 to 5 percent of nanometer silver collosol, 1 to 5 percent of Aloe extract, 0.1 percent of glacial acetic acid and the balance of deionized water, the sum of the mass percent of the above raw materials is 100 percent. The nano-grade gynaecological lotion has characteristic that the lotion can cure gynecology inflammations caused by various pathogenic bacteria, the bacteria killing rate can reach to 100 percent within two minutes, the drug resistance is free from being produced, a sterilization function and an antipruritic effect can be realized, ingredients contained in the lotion can nourish the vagina, the skin on which the inflammations occur can be promoted to heal, and the treatment period can be shortened.

Description

Technical field [0001] The present invention is a pharmaceutical field and involves a non -antibiotic compound Chinese medicine antibacterial and antipruritic solution.Specifically involved all effective ingredients belong to nano -level, does not produce drug resistance, and is suitable for various types of vaginitis and cervicitis treatment methods and preparation methods. Background technique [0002] Gynecological diseases threatened our women's health and showed a trend of younger.According to the relevant information of the health department in my country, the incidence of gynecological diseases in childcare women in my country is more than 70%; women have suffered from vaginitis of different degrees of vaginitis in almost 100%of women in their lives, of which more than 5%have seriously affected normal work and life due to the disease; our country More than 400 million women are involved in gynecological medication.Gynecological inflammation is mainly divided into vaginitis...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K9/107A61P31/04A61P31/10A61P15/02A61P17/04
Inventor 欧阳五庆周莹欧阳伸雨
Owner NORTHWEST A & F UNIV
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