Human skull repairing scaffold and preparation method thereof

Abstract

The invention provides a human skull repairing scaffold which comprises a skull plate formed by a biodegradable polymer and bone growth factors adhered to the surface of the skull plate. The invention also provides a preparation method of the human skull repairing scaffold. After the human skull repairing scaffold provided by the invention is implanted into a human body, the self skull of a patient grows along the surface of the skull plate under the promotion of the bone growth factors, so that the skull injury part heals; because the self skull grows along the surface of the skull plate, the shape of the grown skull coincides with the shape of the original skull, so that malformation and other phenomena are not generated; and in addition, because the skull plate is formed by the biodegradable polymer, after the self skull grows to obtain a complete skull, the skull plate is slowly degraded and discharged out through human body absorption, metabolism and other means, so that the repaired skull injury part is completely formed by the growth of the self skull, no any other foreign bodies are left in the human body, and no any adverse effects are caused to the patient.

Description

technical field [0001] The invention belongs to the technical field of skull repair, in particular to a human skull repair bracket and a preparation method thereof. Background technique [0002] Some brain neurosurgical diseases can cause intracranial high pressure and water, and usually need to remove part of the skull to achieve the purpose of reducing intracranial pressure and saving the patient's life; due to accidental brain trauma, infection, tumor and other diseases, brain surgery is required Surgery can also result in postoperative defects in the patient's skull. Skull defects make the brain tissue unprotected. When the patient lowers his head, the skull defect will cause encephalocele, and when the head is lifted, the brain tissue will collapse at the skull defect. In the case of the forehead, the impact on the patient's appearance and brain tissue is greater. In order to prevent further damage to the brain tissue, restore the airtightness of the cranial cavity, a...

AI Technical Summary

Problems solved by technology

However, it is difficult to shape the titanium alloy mesh, which requires repeated punching; the temperature conductivity of the titanium alloy mesh is strong, and the patient is prone to intracranial discomfort, and it is not easy to fuse with the autologous bone; the edge of the titanium alloy mesh is sharp, and the scalp is thin. Patients are prone to complications such as scalp pain after surgery, and scratching the scalp by the edge of the titanium mesh will cause cerebrospinal fluid leakage or even infection