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Olmesartan medoxomil tablets and preparation method thereof

A technology of olmesartan medoxomil and tablet core, applied in the field of olmesartan medoxomil tablet and its preparation

Active Publication Date: 2011-07-13
FUJIAN TIANQUAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention is proposed for the problem that there is no clinically available olmesartan medoxomil sheet in the prior art, for this reason, the main purpose of the present invention is to provide a kind of olmesartan medoxomil sheet and preparation method, to solve the above problems

Method used

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  • Olmesartan medoxomil tablets and preparation method thereof
  • Olmesartan medoxomil tablets and preparation method thereof
  • Olmesartan medoxomil tablets and preparation method thereof

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Embodiment Construction

[0019] It should be noted that, in the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined with each other. The present invention will be described in detail below with reference to the accompanying drawings and examples.

[0020] Olmesartan medoxomil tablets can be available in three sizes of 5 mg, 20 mg, and 40 mg to facilitate individualized administration according to the patient's condition. In the following implementation with

[0021] 1. Prescription

[0022] 20mg is selected as the specification for research. Through research, it is determined that the prescription of this product is:

[0023] 1. Tablet core prescription:

[0024] Olmesartan Medoxomil 20g

[0025] Lactose① 60g

[0026] Lactose② 30g

[0027] Microcrystalline Cellulose 45g

[0028] PVPK30 5g

[0029] Low-substituted hydroxypropyl cellulose (L-HPC) 8g

[0030] 50% ethanol aqueous solution appropriate amount

[0031] Magnesium Stear...

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Abstract

The invention discloses olmesartan medoxomil tablets and a preparation method thereof. The cores of 1000 olmesartan medoxomil tablets comprise 20g of olmesartan medoxomil, 60-95g of lactose (1), 30g of lactose (2), 45-50g of microcrystalline cellulose, 5g of polyvinylpyrrolidone K30 (PVPK30), 8g of low-substituted hydroxypropyl cellulose (L-HPC), 1g of magnesium stearate and an ethanol water solution for preparing a soft material. The invention solves the problem that no olmesartan medoxomil tablets can be used clinically at present.

Description

technical field [0001] The invention relates to the field of medicines, in particular to an olmesartan medoxomil tablet and a preparation method. Background technique [0002] The number of deaths from cardiovascular diseases is said to be higher than the sum of the other 7 major causes of death (including cancer and AIDS / HIV infection). Hypertension is one of the most prevalent problems in cardiovascular disease and the focus of new drug developers. F&S Market Research Company estimates that the growth of hypertension treatment will stimulate the expansion of the world cardiovascular drug market, and will contribute about 10 percentage points to the total annual growth rate of cardiovascular drugs by 2002. Combined with the need for effective drugs without side effects, the pharmaceutical industry faces a huge opportunity. [0003] Antihypertensive drugs, also known as antihypertensive drugs, refer to drugs that can effectively lower blood pressure and treat hypertension....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/4178A61K47/38A61P9/12
Inventor 邓国权邓志平邓志明邓志清徐广鑫
Owner FUJIAN TIANQUAN PHARMA
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