Sterilizing medicinal ultrasonic coupling agent and preparation method thereof

Abstract

The invention discloses a sterilizing medicinal ultrasonic coupling agent and a preparation method thereof. The sterilizing medicinal ultrasonic coupling agent contains 0.05 to 2 percent of 2,4,4'-trichloro-2'-hydroxydiphenyl ether, 0.1 to 2 percent of R-polysaccharide, 2 to 7 percent of propylene glycol, 2 to 7 percent of glycerol, 0.6 to 1.5 percent of cross-linking polyacrylic resin and 80.5 to 95.25 percent of distilled water; and in addition, triethanolamine which accounts for 0.8 to 1.2 percent of the total weight of the previous mixture is added into the mixture. The preparation method comprises the following steps of: preparing mixed solution of the propylene glycol and the glycerol; fully dissolving the 2,4,4'-trichloro-2'-hydroxydiphenyl ether and the R-polysaccharide into the prepared mixed solution; preparing cross-linking polyacrylic resin solution; adding the prepared mixed solution into the cross-linking polyacrylic resin solution to form a gelatinous macromolecular substance; and dripping triethanolamine solution into the gelatinous macromolecular substance to obtain neutral ultrasonic coupling agent. The sterilizing medicinal ultrasonic coupling agent thoroughly solves the problem that effective sterilization cannot be realized in short time, and is suitable for sterilizing the skin and the mucosa.

Description

technical field [0001] The invention relates to the preparation of a coupling agent between a medical therapeutic instrument probe and human skin, in particular to a disinfecting and sterilizing medical ultrasonic coupling agent and a preparation method thereof. Background technique [0002] The function of the traditional medical ultrasonic coupling agent is to strengthen the coupling between the ultrasonic probe and human skin, to isolate the air between the ultrasonic probe and the skin of the inspected part, so that the sound wave conduction is not affected by the air and attenuated, so as to achieve a good detection effect . The "preparation method of medical ultrasonic coupling agent" disclosed by CN1087016A is to first take 5 grams of CPB-1 series acrylic acid polymer (i.e. Carboresin-1 type substance) and put it into water for 5-6 hours, after making it expand, add 20% hydrogen The sodium oxide solution was used to make the pH value between 6.8 and 7.2, then sodium ...

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Problems solved by technology

[0003] (1) There is no suitable compound, and the particularity of the ultrasonic probe material determines that most of the disinfectants on the market that are corrosive and swellable to this plastic and rubber cannot be used for the disinfection of ultrasonic probes;

[0004] (2) There is no suitable medium, and the particularity of the structure of the ultrasonic probe makes it impossible to use the most commonly used soaking method for disinfection, and the requirements for the medium are high;

[0005] (3) Disinfection time, due to the high frequency of work, the interval between the tested patients is very short, usually about 1 minute. Disinfectants that can simultaneously kill bacteria, mold and viruses in such a short period of time are not yet on the market.

Under such limited conditions, it is not enough to use only 2,4,4'-trichloro-2'-hydroxydiphenyl ether to kill bacteria, molds and viruses, and it cannot achieve the disinfection and sterilization medical ultrasonic coupling agent. Skin disinfection, but also suitable for mucous membrane disinfection requirements

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